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HAUS2

  • Official Full Name

    HAUS augmin-like complex, subunit 2

  • Overview

    HAUS2 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified;in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a;microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic;spindle assembly (Goshima et al., 2008 (PubMed 18443220); Uehara et al., 2009 (PubMed 19369198)).
  • Synonyms

    HAUS2; HAUS augmin-like complex, subunit 2; C15orf25, centrosomal protein 27kDa , CEP27, chromosome 15 open reading frame 25; HAUS augmin-like complex subunit 2; FLJ10460; HsT17025; C15orf25; Centrosomal protein 27 kDa; Chromosome 15 open reading frame 25; centrosomal protein 27kDa; centrosomal protein of 27 kDa; CEP27;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HAUS2-5173H Recombinant Human HAUS2 Protein, GST-tagged Wheat Germ GST
Human HAUS2-5629HCL Recombinant Human HAUS2 293 Cell Lysate HEK293 N/A
Human HAUS2-3826HF Recombinant Full Length Human HAUS2 Protein, GST-tagged In Vitro Cell Free System GST 235 amino acids
Human HAUS2-828H Recombinant Human HAUS2 Protein, His-tagged E.coli His
Mouse HAUS2-7490M Recombinant Mouse HAUS2 Protein Mammalian Cell His
Mouse HAUS2-4064M-B Recombinant Mouse HAUS2 Protein Pre-coupled Magnetic Beads HEK293
Mouse HAUS2-4064M Recombinant Mouse HAUS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HAUS2-2038R Recombinant Rhesus monkey HAUS2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HAUS2-1859R Recombinant Rhesus Macaque HAUS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HAUS2-1859R-B Recombinant Rhesus Macaque HAUS2 Protein Pre-coupled Magnetic Beads HEK293
Chicken HAUS2-4451C Recombinant Chicken HAUS2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HAUS2 involved in several pathways and played different roles in them. We selected most pathways HAUS2 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAUS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Anchoring of the basal body to the plasma membraneIQCB1;CKAP5;CEP89;ODF2;OFD1;CSNK1D;MAPRE1;CCP110;RAB3IP
Assembly of the primary ciliumEXOC5;PROL1;SETD6;CEP78;WDR35;DCTN3;TTC21B;TTC30A1;CCT8
Cell CycleSYNE1;DBF4;ANKLE2;DCTN1A;STAG1;RBBP7;MAPRE1A;CETN2;PDS5A
Cell Cycle, MitoticB9D2;ERCC6L;GINS2;CENPK;NUPL2;ZWILCH;TMEM188;CEP63;TUBGCP2
Centrosome maturationCKAP5;CEP70;CEP63;CETN2;ACTR1A;NUMA1;HAUS2;CEP57;DCTN1
G2/M TransitionTUBGCP3;CEP76;CP110;CEP290;MYBL2;MAPRE1A;FOXM1;TUBG2;CDK11A
Loss of Nlp from mitotic centrosomesHAUS2;SSNA1;OFD1;DCTN1A;CEP164;MAPRE1;NDE1;CP110;TSGA14
Loss of proteins required for interphase microtubule organizationfrom the centrosomeSDCCAG8;CEP57;MAPRE1;TSGA14;CEP164;DCTN1A;SSNA1;CEP72;NEDD1

HAUS2 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by HAUS2 itself. We selected most functions HAUS2 had, and list some proteins which have the same functions with HAUS2. You can find most of the proteins on our site.

Function Related Protein
molecular_functionMFSD12;GM106;FADS3;RTN1A;PBLD1;SRRD;TMEFF1B;TMEM143;TPM4B

HAUS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAUS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAUS2.

Haus4; Haus1; HAUS5; HAUS3; HAUS6; HAUS1; HAUS7; HAUS8; HAUS4; Haus6; MAPK6

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