HIST1H1A Protein, histone cluster 1, H1a

HIST1H1A

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HIST1H1A

Official Full Name histone cluster 1, H1a
Background Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Synonyms HIST1H1A; histone cluster 1, H1a; H1 histone family, member 1 , H1F1, histone 1, H1a; histone H1.1; H1.1; H1 histone family member 1; H1F1; HIST1; Histone 1 H1a; Histone cluster 1 H1a; histone 1, H1a; H1 histone family, member 1; H1A
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Mouse
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse HIST1H1A-552M Recombinant Mouse HIST1H1A Protein (2-213 aa), GST-tagged E.coli GST
    Human DMABT-H16577 Mouse Anti-HisT1H1A Monoclonal Antibody Mouse N/A
    Human HIST1H1A-231H Recombinant Human HIST1H1A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human HIST1H1A-4773H Recombinant Human HIST1H1A Protein, GST-tagged Wheat Germ GST
    Human HIST1H1A-5555HCL Recombinant Human HIST1H1A 293 Cell Lysate HEK293 N/A
    Mouse HIST1H1A-7642M Recombinant Mouse HIST1H1A Protein Mammalian Cell His
    Rat HIST1H1A-2848R Recombinant Rat HIST1H1A Protein Mammalian Cell His
    Rhesus Macaque HIST1H1A-2085R Recombinant Rhesus monkey HIST1H1A Protein, His-tagged Mammalian Cell His

    HIST1H1A involved in several pathways and played different roles in them. We selected most pathways HIST1H1A participated on our site, such as Activation of DNA fragmentation factor, Apoptosis, Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of DNA fragmentation factor HMGB2A; HMGB2; HIST1H1A; DFFA; HIST1H1D; HIST1H1C; H1F0; HIST1H1B; HIST1H1E
    Apoptosis PIK3CD; CAPN1A; TRAF2; CAPN2L; DSG1; IRAK4; BIDA; FADD; PRKACA; DSP
    Apoptosis induced DNA fragmentation H1F0; HIST1H1A; HMGB2A; HIST1H1C; HMGB2; HIST1H1B; HIST1H1E; HIST1H1D; DFFA
    Apoptotic execution phase SPNA2; DNM1L; SATB1; STK24; DFFA; DSP; OCLN; LMNB1; CLSPN; PLEC
    Cellular Senescence CDKN2A; TERF2; KAT5; HIRA; EHMT2; HIST2H3C; HMGA1-RS1; HIST1H1B; PHC2; RING1
    Cellular responses to stress AGO1; ACD; MINK1; C7orf59; TXN; TERF2; HIST1H1E; HSBP1A; CDKN2D; HSBP1B
    DNA Damage/Telomere Stress Induced Senescence HMGA1-RS1; EP400; TERF2; HIST1H1C; HIST1H1D; HIST1H1B; H1F0; HIRA; TERF2IP; POT1A
    Formation of Senescence-Associated Heterochromatin Foci (SAHF) HIRA; CABIN1; HIST1H1B; HIST1H1D; HIST1H1E; HIST1H1C; UBN1; EP400; ASF1A; HMGA1B

    HIST1H1A has several biochemical functions, for example, chromatin DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H1A itself. We selected most functions HIST1H1A had, and list some proteins which have the same functions with HIST1H1A. You can find most of the proteins on our site.

    Function Related Protein
    chromatin DNA binding VAX2; RELA; SMAD3; SLAMF7; VAX1; BCL6; GRHL2; APEX1; H1F0; ATOH1
    protein binding UTP3; KLK13; SUGP1; BLM; NEK11; MAST2; CYTIP; SPATA8; TPD52L1; PAQR5

    HIST1H1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H1A here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H1A.

    SIR2rp1; ADPRH; TERF1; WHSC1L1; TERF2IP; Npro; midostaurin; d2cfj1_9flav; ssrna_ag; CBX4; P/V/C; DFFB; MYC; lt_sv40; NS; NS

    Wang, ZF; Sirotkin, AM; et al. The mouse histone H1 genes: Gene organization and differential regulation. JOURNAL OF MOLECULAR BIOLOGY 271:124-138(1997).

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