hist1h2al
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  • Official Full Name
  • histone cluster 1, H2al
  • Background
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
  • Synonyms
  • HIST1H2AL; histone cluster 1, H2al; H2A histone family, member I , H2AFI, histone 1, H2al; histone H2A type 1; dJ193B12.9; H2A/i; H2A histone family member I; H2A.1; H2A.i; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AM; Histone 1 H2al; Histone 1 H2am; Histone cluster 1 H2al; Histone H2A/p; histone 1, H2al; histone 1, H2am; H2A histone family, member I
Cat.#:HIST1H2AL-121HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIST1H2AL Protein, HIS-tagged
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Cat.#:HIST1H2AL-326HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human HIST1H2AL lysate
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Involved Pathway

HIST1H2AL involved in several pathways and played different roles in them. We selected most pathways HIST1H2AL participated on our site, such as Alcoholism, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIST1H2AL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
GNG8; HIST1H2BD; H2AFY; NPY; SLC29A1; BRAF; GM14478; HIST1H3F; KRAS; CAMK4
Systemic lupus erythematosus
H2AFZ; HLA-DRB3; H2AFJ; GM14479; H2AFB1; HIST1H4G; GM14478; IFNG; TROVE2; HIST2H2AC

Protein Function

HIST1H2AL has several biochemical functions, for example, DNA binding, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIST1H2AL itself. We selected most functions HIST1H2AL had, and list some proteins which have the same functions with HIST1H2AL. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZEB2B; TRERF1; BHLHA15; ZFP35; HOXA10B; HOXC12; PRDM2; SIX6B; ASCL1; HOXD11A
Function enzyme binding
Related Protein TSPAN17; PLCE1; PCCA; MAP2K7; ATXN10; TSPAN14; DNMT3L; U2AF2; TSPAN33; HIST1H2AL
Function protein binding
Related Protein PPIC; TTC3; CASP8; PTGIS; SLC3A1; SMARCD1; FAM113B; SYN1; NUP85; PARP16
Function protein heterodimerization activity
Related Protein MICU1; BARD1; HNF1B; SPNA1; PIK3R2; SCGB2A1; BAK1; BCL2L10; HIST1H2AB; CEBPA

Interacting Protein

HIST1H2AL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIST1H2AL here. Most of them are supplied by our site. Hope this information will be useful for your research of HIST1H2AL.
BRPF1; YWHAZ; IL33; q9dum3_hhv8; RYBP; TERF2IP; NS