hnrnpm
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  • Official Full Name
  • heterogeneous nuclear ribonucleoprotein M
  • Background
  • This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • HNRNPM; heterogeneous nuclear ribonucleoprotein M; HNRPM, NAGR1; CEA receptor; CEAR; HNRNPM4; HNRPM4; HTGR1; hnRNA-binding protein M4; N-acetylglucosamine receptor 1; heterogenous nuclear ribonucleoprotein M4; HNRPM; NAGR1; hnRNP M; DKFZp547H118
Cat.#:HNRNPM-1244HTag:His-SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPM Protein, His-SUMO-tagged
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Cat.#:HNRNPM-5432HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HNRNPM protein, His-tagged
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Cat.#:HNRNPM-5438HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HNRNPM protein, GST-tagged
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Cat.#:HNRNPM-2621CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HNRNPM
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Cat.#:HNRNPM-8171ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HNRNPM
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Cat.#:HNRNPM-5440HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HNRNPM 293 Cell Lysate
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Involved Pathway

HNRNPM involved in several pathways and played different roles in them. We selected most pathways HNRNPM participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with HNRNPM were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
HSP70; SRSF10; U2AF2B; FAM120B; SF3B2; PRPF38A; PPIL1; SART1; DHX8; THOC3

Protein Function

HNRNPM has several biochemical functions, for example, RNA binding, antigen binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HNRNPM itself. We selected most functions HNRNPM had, and list some proteins which have the same functions with HNRNPM. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein CPSF2; RBM48; PCBP2; ZNF385C; NOL3; LIN28A; PUS7L; ENDOU; RNASEL2; PPP1R8
Function antigen binding
Related Protein LILRA1; TOPORS; LAG3; IGKV1-5; LILRA3; IGHM; SPON2; LILRB4; TSPAN4; KIR2DL3
Function nucleotide binding
Related Protein PABPC1; cka1; CDC34A; AKT3A; RBM39; UCK2B; RAB1BB; APOA1BP; PRKG1A; TGFBR1A
Function poly(A) RNA binding
Related Protein HIST1H4B; SNRNP40; PRAC; ZNF326; FAM120B; PTCD2; SF3A3; SRSF11; CIRBP; DDX28
Function protein binding
Related Protein ZNF576; NEK2; TARSL2; ALAS1; DZIP1L; HIST1H4I; AZI2; SP100; ATL2; SLX4IP
Function protein domain specific binding
Related Protein HOMER2; GABRR1; ARFIP1; IKBKG; IST1; ATN1; PPARA; CHMP2B; STAMBP; DDC

Interacting Protein

HNRNPM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HNRNPM here. Most of them are supplied by our site. Hope this information will be useful for your research of HNRNPM.
LMO2; CDC5L; PLRG1; 4005; HNRNPF