hoxa11
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  • Official Full Name
  • homeobox A11
  • Background
  • In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008]
  • Synonyms
  • HOXA11; homeobox A11; HOX1; HOX1I; homeobox protein Hox-A11; homeo box 1I; homeobox protein HOXA11; homeobox protein Hox-1I;
Cat.#:HOXA11-4940HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HOXA11 Protein, GST-tagged
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Cat.#:HOXA11-095HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HOXA11 Protein, GST-HIS-tagged
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Cat.#:HOXA11-7786MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HOXA11 Protein
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Cat.#:HOXA11-6187CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HOXA11
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Cat.#:HOXA11-5428HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HOXA11 293 Cell Lysate
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Involved Pathway

HOXA11 involved in several pathways and played different roles in them. We selected most pathways HOXA11 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXA11 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Transcriptional misregulation in cancer
BMP2K; HIST1H3E; FCGR1A; TP53; MAF; NTRK1; WNT16; SSX2; LYL1; NUPR1

Protein Function

HOXA11 has several biochemical functions, for example, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA11 itself. We selected most functions HOXA11 had, and list some proteins which have the same functions with HOXA11. You can find most of the proteins on our site.
Function
Related Protein
Function sequence-specific DNA binding
Related Protein HOXA3; HLFA; ZBTB49; RAD21A; VRTN; GTF2E1; FOXO6; HOXC4; RORAB; NKX2.4A

Interacting Protein

HOXA11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA11 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA11.
PGBD3