hoxa13
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  • Official Full Name
  • homeobox A13
  • Background
  • In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
  • Synonyms
  • HOXA13; homeobox A13; homeo box A13 , HOX1, HOX1J; homeobox protein Hox-A13; Homeo box 1J; Homeo box A13; Homeobox 1J; Homeobox protein Hox A13; Homeobox protein Hox-1J; Homeobox protein HOXA13; Homeobox1J; HomeoboxA13; HOX 1; HOX 1J; Hox 1J protein; HOX A13; HOX1; HOX1J; HOXA 13; HXA13_HUMAN; Transcription factor HOXA13; OTTHUMP00000217287
Cat.#:HOXA13-4942HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HOXA13 Protein, GST-tagged
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Cat.#:HOXA13-28510THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human HOXA13
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Cat.#:HOXA13-7787MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HOXA13 Protein
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Cat.#:HOXA13-5715CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HOXA13
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Protein Function

HOXA13 has several biochemical functions, for example, DNA binding, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA13 itself. We selected most functions HOXA13 had, and list some proteins which have the same functions with HOXA13. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF689; HIST1H111R; ATF4B1; FUS; FOXP1A; MIER2; POGK; NPAS4A; JARID2B; ZFP775
Function sequence-specific DNA binding
Related Protein POU5F3; HOXB8A; HOXD4; NKX2.2A; BSX; NOTCH1; HMX2; GATA5; RX1; SPIB
Function transcription factor activity, sequence-specific DNA binding
Related Protein TEAD3B; DDIT3; TRP63; KLF9; ZNF92; HOXC5A; SIM1; SALL1; RXRA; ELK4
Function transcription regulatory region DNA binding
Related Protein NR5A2; TAF7L; ZFP382; HNF1A; ARID5A; FOXA1; GABPB2; MESP1; TOMM20A; THRA

Interacting Protein

HOXA13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA13 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA13.
AIM2; PYHIN1

HOXA13 Related Articles

Palmieri, C; Riccardi, E; et al. Immunohistochemical Expression of HOXA-13 in Normal, Hyperplastic and Neoplastic Canine Prostatic Tissue. JOURNAL OF COMPARATIVE PATHOLOGY 149:417-423(2013).
Stadler, HS; Higgins, KM; et al. Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs. DEVELOPMENT 128:4177-4188(2001).