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HSD17B1

  • Official Full Name

    hydroxysteroid (17-beta) dehydrogenase 1

  • Overview

    Estradiol 17-beta-dehydrogenase 1 is an enzyme that in humans is encoded by the HSD17B1 gene.
  • Synonyms

    HSD17B1; hydroxysteroid (17-beta) de-hydrogenase 1; HSD17; EDHB17; EDH17B2; SDR28C1; MGC138140; estradiol 17-beta-dehydrogenase 1; E2DH; 20-alpha-HSD; 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 1; placental 17-beta-hydroxysteroid dehydrogenase; hydroxyster-oid (17-beta) dehydrogenase 1 isoform; short chain dehydrogenase/reductase family 28CE, member 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSD17B1-27735TH Recombinant Human HSD17B1 Wheat Germ N/A 97 amino acids
Human HSD17B1-586H Recombinant Human hydroxysteroid (17-beta) dehydrogenase 1, His-tagged E.coli His
Human HSD17B1-5062H Recombinant Human HSD17B1 Protein, GST-tagged Wheat Germ GST
Human HSD17B1-145HFL Recombinant Full Length Human HSD17B1 Protein, N-His-tagged E.coli His
Human HSD17B1-3290H Recombinant Human HSD17B1 protein, His-tagged E.coli His 191 - 328 aa
Human HSD17B1-2404H Recombinant Human HSD17B1 Protein (Thr4-Pro289), N-His tagged E.coli N-His Thr4-Pro289
Human HSD17B1-3804HF Recombinant Full Length Human HSD17B1 Protein, GST-tagged In Vitro Cell Free System GST 328 amino acids
Human HSD17B1-603HFL Recombinant Full Length Human HSD17B1 Protein, C-Flag-tagged Mammalian cells Flag
Human HSD17B1-1100H-B Recombinant Human HSD17B1 Protein Pre-coupled Magnetic Beads HEK293
Human HSD17B1-1100H Recombinant Human HSD17B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSD17B1-7871M Recombinant Mouse HSD17B1 Protein Mammalian Cell His
Mouse HSD17B1-4332M-B Recombinant Mouse HSD17B1 Protein Pre-coupled Magnetic Beads HEK293
Mouse HSD17B1-4332M Recombinant Mouse HSD17B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hsd17b1-1177M Recombinant Mouse Hsd17b1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat HSD17B1-2922R Recombinant Rat HSD17B1 Protein Mammalian Cell His
Rat HSD17b1-3256R Recombinant Rat HSD17b1 protein, His-SUMO-tagged E.coli His-SUMO Met1~Ile344
Rat HSD17B1-2577R Recombinant Rat HSD17B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HSD17B1-2577R-B Recombinant Rat HSD17B1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HSD17B1-2152R Recombinant Rhesus monkey HSD17B1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSD17B1-1973R-B Recombinant Rhesus Macaque HSD17B1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HSD17B1-1973R Recombinant Rhesus Macaque HSD17B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HSD17B1-11624Z Recombinant Zebrafish HSD17B1 Mammalian Cell His
Chicken HSD17B1-6400C Recombinant Chicken HSD17B1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HSD17B1 involved in several pathways and played different roles in them. We selected most pathways HSD17B1 participated on our site, such as Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Steroid hormone biosynthesisSRD5A1;CYP2C39;UGT1A6B;HSD17B6;CYP2C70;CYP3A7;HSD3B1;CYP3A25;HSD17B7
Metabolic pathwaysSUCLG2;GLUL;PRIM1;AOX4;SGMS1;ACMSD;OLAH;AGPAT3;MECR
Ovarian steroidogenesisPRKACG;STAR;ALOX5;HSD17B2;HSD3B5;PRKACA;HSD3B2;INS2;Adcy4

HSD17B1 has several biochemical functions, for example, catalytic activity, estradiol 17-beta-dehydrogenase activity, testosterone dehydrogenase (NAD+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B1 itself. We selected most functions HSD17B1 had, and list some proteins which have the same functions with HSD17B1. You can find most of the proteins on our site.

Function Related Protein
catalytic activityHSD17B1;PARP3;PNP6;TDH2;SCP2A;PNP4B;DPYDB;GLULB;AADAC
estradiol 17-beta-dehydrogenase activityAKR1C6;HSD17B7;HSD17B12;HSD17B2;HSD17B6;HSD17B12B;RDH8A;HSD17B12A;HSD17B14
testosterone dehydrogenase (NAD+) activityHSD17B2;AKR1C3;HSD17B6;HSD17B8;HSD17B1;H2-KE6;DHRS9

HSD17B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B1.

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