hsd17b1
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  • Official Full Name
  • hydroxysteroid (17-beta) dehydrogenase 1
  • Background
  • Estradiol 17-beta-dehydrogenase 1 is an enzyme that in humans is encoded by the HSD17B1 gene.
  • Synonyms
  • HSD17B1; hydroxysteroid (17-beta) de-hydrogenase 1; HSD17; EDHB17; EDH17B2; SDR28C1; MGC138140; estradiol 17-beta-dehydrogenase 1; E2DH; 20-alpha-HSD; 17-beta-HSD 1; 20 alpha-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 1; placental 17-beta-hydroxysteroid dehydrogenase; hydroxyster-oid (17-beta) dehydrogenase 1 isoform; short chain dehydrogenase/reductase family 28CE, member 1
Cat.#:HSD17B1-5062HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HSD17B1 Protein, GST-tagged
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Cat.#:HSD17B1-27735THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human HSD17B1
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Cat.#:HSD17B1-586HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human hydroxysteroid (17-beta) dehydrogenase 1, His-tagged
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Cat.#:HSD17B1-7871MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HSD17B1 Protein
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Cat.#:HSD17B1-2922RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HSD17B1 Protein
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Cat.#:HSD17B1-2152RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HSD17B1 Protein, His-tagged
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Cat.#:HSD17B1-6400CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HSD17B1
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Cat.#:HSD17B1-11624ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HSD17B1
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Involved Pathway

HSD17B1 involved in several pathways and played different roles in them. We selected most pathways HSD17B1 participated on our site, such as Steroid hormone biosynthesis, Metabolic pathways, Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Steroid hormone biosynthesis
UGT1A3; SRD5A3; AKR1C2; PPP1R2; CYP3A25; CYP2C38; HSD17B7; UGT1A6B; UGT1A7; UGT2B7
Metabolic pathways
NMNAT2; UGT1A2; HPSE; AK7B; HSD11B1; TCIRG1; COASY; NDUFA5; MOGS; CYP2J5
Ovarian steroidogenesis
HSD3B5; HSD17B2; HSD17B7; STAR; INS1; CYP2J5; HSD3B6; GNAS; INS; LHB

Protein Function

HSD17B1 has several biochemical functions, for example, catalytic activity, estradiol 17-beta-dehydrogenase activity, testosterone dehydrogenase (NAD+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B1 itself. We selected most functions HSD17B1 had, and list some proteins which have the same functions with HSD17B1. You can find most of the proteins on our site.
Function
Related Protein
Function catalytic activity
Related Protein TIGARB; PPM1BA; TDH2; PNP5A; PGAM1A; SLC3A2; AOX3; LYZ1; AADAC; PCYT1BA
Function estradiol 17-beta-dehydrogenase activity
Related Protein HSD17B12A; HSD17B7; HSD17B12; HSD17B1; H2-KE6; HSD17B8; RDH8B; HSD17B14; HSD17B11; HSD17B6
Function testosterone dehydrogenase (NAD+) activity
Related Protein AKR1C3; HSD17B6; H2-KE6; HSD17B2; DHRS9; HSD17B1; HSD17B8