HSPA13 Protein, heat shock protein 70kDa family, member 13

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HSPA13

Official Full Name	heat shock protein 70kDa family, member 13
Background	The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein.
Synonyms	HSPA13; heat shock protein 70kDa family, member 13; STCH, stress 70 protein chaperone, microsome associated, 60kD , stress 70 protein chaperone, microsome associated, 60kDa; heat shock 70 kDa protein 13; HSP13_HUMAN; MGC133835; Microsomal stress 70 protein ATPase core; Microsomal stress-70 protein ATPase core; Stress 70 protein chaperone microsome associated 60 kDa protein; Stress-70 protein chaperone microsome-associated 60 kDa protein; stress 70 protein chaperone, microsome-associated, 60kD; stress 70 protein chaperone, microsome-associated, 60kDa; STCH

Species :
Chicken
Human
Mouse
Rat
Rhesus Macaque
Zebrafish

Source :
E.coli
HEK293
HEK293T
Mammalian Cell

Tag :
GST
His
MYC/DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Mouse	Hspa13-489M	Recombinant Mouse Hspa13 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK
Human	HSPA13-5133H	Recombinant Human HSPA13 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK
Human	HSPA13-13982H	Recombinant Human HSPA13, GST-tagged	E.coli	GST
Human	HSPA13-3408H	Recombinant Human HSPA13, His-tagged	E.coli	His
Human	HSPA13-5358HCL	Recombinant Human HSPA13 293 Cell Lysate	HEK293	N/A
Mouse	HSPA13-7902M	Recombinant Mouse HSPA13 Protein	Mammalian Cell	His
Rat	HSPA13-2942R	Recombinant Rat HSPA13 Protein	Mammalian Cell	His
Rhesus Macaque	HSPA13-2163R	Recombinant Rhesus monkey HSPA13 Protein, His-tagged	Mammalian Cell	His
Chicken	HSPA13-2492C	Recombinant Chicken HSPA13	Mammalian Cell	His
Zebrafish	HSPA13-5584Z	Recombinant Zebrafish HSPA13	Mammalian Cell	His

Involved Pathway Protein Function Interacting Protein HSPA13 Related Articles

HSPA13 involved in several pathways and played different roles in them. We selected most pathways HSPA13 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPA13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cellular response to heat stress	HDAC6; NUPL2; NUP50; HSBP1A; HSPA13; DNAJC2; HSBP1; RPS19BP1; DNAJB6; BAG3
Cellular responses to stress	EHMT2; MOV10; SCMH1; PHC1; HSPA12B; HSBP1A; BMI1B; C7orf59; RING1; TERF2
Regulation of HSF1-mediated heat shock response	DNAJC7; BAG5; HSPA12B; HSPH1; DNAJC2; HSPA13; ST13; RPS19BP1; HSPA7; DNAJB6

HSPA13 has several biochemical functions, for example, ATP binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPA13 itself. We selected most functions HSPA13 had, and list some proteins which have the same functions with HSPA13. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	DHX30; SCYL3; EPHA6; AK9; PTK6B; DDX41; UBE2L3A; BUB1B; TOR1L3; KITB
protein binding	PKP4; NSL1; FREM2; MAP6; RUNDC3A; POLR1C; NLGN4X; EXOC1; MAPKBP1; pab1

HSPA13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPA13 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPA13.

UBQLN1; SGTA; UBQLN1; SSR1; BAG6; RMI1; POLE4; UBQLN4; cona_canen; env

Brown, CA; Schmidt, C; et al. In vitro screen of prion disease susceptibility genes using the scrapie cell assay. HUMAN MOLECULAR GENETICS 23:5102-5108(2014).

Zhu, YF; Ren, CL; et al. Gene expression of Hsp70, Hsp90 and Hsp110 families in normal palate and cleft palate during mouse embryogenesis. TOXICOLOGY AND INDUSTRIAL HEALTH 29:915-930(2013).

Lloyd, SE; Mead, S; et al. Genetics of prion diseases. CURRENT OPINION IN GENETICS & DEVELOPMENT 23:345-351(2013).

Grizenkova, J; Akhtar, S; et al. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:13722-13727(2012).

HSPA13 Protein, heat shock protein 70kDa family, member 13

HSPA13

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