hck
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  • Official Full Name
  • hemopoietic cell kinase
  • Background
  • Hck is a member of the Src family of non-receptor tyrosine kinases involved in the modulation of a wide variety of normal and pathogenic cellular processes including growth, development, differentiation, and carcinogenesis. These proteins contain a consen
  • Synonyms
  • HCK; hemopoietic cell kinase; tyrosine-protein kinase HCK; JTK9; p59-HCK/p60-HCK; hematopoietic cell kinase; p59Hck; p61Hck
Cat.#:HCK-1057HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human HCK Protein, MYC/DDK-tagged
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Cat.#:HCK-4625HTag:GST|His
Source (Host):Insect CellSpecies:Human
Product nameRecombinant Human HCK Protein, GST-His-tagged
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Cat.#:HCK-4626HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HCK Protein, GST-tagged
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Cat.#:HCK-29189THTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HCK, GST-tagged
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Cat.#:HCK-7854HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HCK protein, His & T7-tagged
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Cat.#:Hck-7855MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hck protein, His & T7-tagged
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Cat.#:HCK-2805RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HCK Protein
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Cat.#:HCK-171HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Hemopoietic Cell Kinase, SH3 Domain, GST-tagged
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Cat.#:HCK-327HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Hemopoietic Cell Kinase, GST-tagged, Active
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Cat.#:HCK-1235HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Hemopoietic Cell Kinase, His-tagged
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Cat.#:HCK-1412HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human HCK (Active), GST-tagged
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Cat.#:HCK-774HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human HCK cell lysate
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Cat.#:Kit-1599Tag:N/A
Source (Host):Species:
Product nameHCK Kinase Binding Assay Kit
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Involved Pathway

HCK involved in several pathways and played different roles in them. We selected most pathways HCK participated on our site, such as Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chemokine signaling pathway
NFKBIA; CXCR5; VAV3; CXCL13; GNAI2; CCL24; GNG10; BCAR1; GNG5; JAK2
Fc gamma R-mediated phagocytosis
WASF3; AMPH; PTPRC; RPS6KB1; MAP2K1; FCGR1A; ARF6; ASAP3; CFL2; PLA2G6

Protein Function

HCK has several biochemical functions, for example, ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HCK itself. We selected most functions HCK had, and list some proteins which have the same functions with HCK. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein NEK6; ITPKB; ATP7B; PLK5; PDK2; SLC27A5; DYNC1H1; PFKMB; CAMK4; PRKCQ
Function non-membrane spanning protein tyrosine kinase activity
Related Protein CSK; JAK1; TNK2; ZAP70; FER; FES; ITK; YES1; PTK2BB; JAK3
Function protein binding
Related Protein INTS12; LENG1; C7orf31; RARRES2; RBMY1F; DBC1; RINT1; HNF4A; ZP3; PAX8
Function protein tyrosine kinase activity
Related Protein FGFR4; TYK2; DYRK4; JAK2A; NTRK3A; TYRO3; EPHB4A; FGFR1B; CLK4; DYRK1A
Function receptor binding
Related Protein YES1; NUDT7; SLC27A2; EFNA1; JAK2; CD276; LPL; ALCAM; Ifnl2; ADM

Interacting Protein

HCK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCK here. Most of them are supplied by our site. Hope this information will be useful for your research of HCK.
KHDRBS1; polg_hcvh; WAS; SOS1

HCK Related Articles

Stegeman, H; Kaanders, JHAM; et al. Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines. MOLECULAR CANCER 12:-(2013).
Ben-Zimra, M; Bachelet, I; et al. Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-beta 1. ALLERGY 68:1259-1268(2013).