Recombinant Human HCK Protein, GST-tagged

• Cat.No.: HCK-4626H
• Product Overview: Human HCK full-length ORF ( AAH14435, 1 a.a. - 505 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 81.29 kDa
• AA Sequence: MGCMKSKFLQVGGNTSSKTETSASP HCPVYVPDPTSTIKPGPNSHNSNTP GIREAGSEDIIVVALYDYEAIHHED LSFQKGDQMVVLEESGEWWKARSLA TRKEGYIPSNYVARVDSLETEEWFF KGISRKDAERQLLAPGNMLGSFMIR DSETTKGSYSLSVRDYDPRQGDTVK HYKIRTLDNGGFYISPRSTFSTLQE LVDHYKKGNDGLCQKLSVPCMSSKP QKPWEKDAWEIPRESLKLEKKLGAG QFGEVWMATYNKHTKVAVKTMKPGS MSVEAFLAEANVMKTLQHDKLVKLH AVVTKEPIYIITEFMAKGSLLDFLK SDEGSKQPLPKLIDFSAQIAEGMAF IEQRNYIHRDLRAANILVSASLVCK IADFGLARVIEDNEYTAREGAKFPI KWTAPEAINFGSFTIKSDVWSFGIL LMEIVTYGRIPYPGVSNPEVIRALE RGYRMPRPENCPEELYNIMMRCWKN RPEERPTFEYIQSVLDDFYTATESQ YQQQP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HCK hemopoietic cell kinase [ Homo sapiens ]
• Official Symbol: HCK
• Synonyms: HCK; hemopoietic cell kinase; tyrosine-protein kinase HCK; JTK9; p59-HCK/p60-HCK; hematopoietic cell kinase; p59Hck; p61Hck
• Gene ID: 3055
• mRNA Refseq: NM_001172129
• Protein Refseq: NP_001165600
• MIM: 142370
• UniProt ID: P08631