Hmox2 Protein, heme oxygenase (decycling) 2


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Official Full Name heme oxygenase (decycling) 2
Background Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Synonyms HMOX2; heme oxygenase (decycling) 2; HO-2; heme oxygenase 2;
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HMOX2-021H Recombinant Human HMOX2 Protein, His-tagged E.coli His
    Mouse Hmox2-1142M Recombinant Mouse Hmox2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human HMOX2-1343H Recombinant Human Heme Oxygenase (Decycling) 2 Human N/A
    Human HMOX2-13856H Recombinant Human HMOX2, His-tagged E.coli His
    Human HMOX2-1453H Recombinant Human Heme Oxygenase (Decycling) 2, GST-tagged E.coli GST
    Human HMOX2-2616H Recombinant Human HMOX2 protein, His & T7-tagged E.coli His/T7
    Human HMOX2-27003TH Recombinant Human HMOX2 E.coli N/A
    Human HMOX2-27005TH Recombinant Human HMOX2 E.coli N/A
    Human HMOX2-4886H Recombinant Human HMOX2 Protein, GST-tagged Wheat Germ GST
    Human HMOX2-5466HCL Recombinant Human HMOX2 293 Cell Lysate HEK293 N/A
    Mouse Hmox2-2617M Recombinant Mouse Hmox2 protein, His & T7-tagged E.coli His/T7
    Mouse HMOX2-7744M Recombinant Mouse HMOX2 Protein Mammalian Cell His
    Rat Hmox2-2134R Recombinant Rat Heme Oxygenase (Decycling) 2 E.coli N/A
    Rat HMOX2-2873R Recombinant Rat HMOX2 Protein Mammalian Cell His
    Cynomolgus Monkey HMOX2-591C Recombinant Cynomolgus HMOX2 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque HMOX2-2111R Recombinant Rhesus monkey HMOX2 Protein, His-tagged Mammalian Cell His

    Hmox2 involved in several pathways and played different roles in them. We selected most pathways Hmox2 participated on our site, such as Porphyrin and chlorophyll metabolism, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with Hmox2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Porphyrin and chlorophyll metabolism UGT2A2; BLVRA; HEPH; UROD; UGT1A6B; BLVRB; FXN; HMOX2; FECH; UGT1A6A
    Mineral absorption SLC8A1; ATOX1; SLC40A1; ATP7A; ATP1A2; S100G; SLC34A2; FXYD2; FTH1; Trf

    Hmox2 has several biochemical functions, for example, heme oxygenase (decyclizing) activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Hmox2 itself. We selected most functions Hmox2 had, and list some proteins which have the same functions with Hmox2. You can find most of the proteins on our site.

    Function Related Protein
    heme oxygenase (decyclizing) activity HMOX2A; HMOX1A; HMOX1; HMOX2; HMOX1B
    metal ion binding CNOT8; LMAN1; BTR02; TSNAX; RARGB; PDXK; ZBBX; ZFP518A; KDM6BB; ZNF654
    protein binding BIN1; GADD45B; DIXDC1; ZC3H11A; HIST1H4K; SERPINB5; IL17F; MRPS12; MLLT10; SIRPG

    Hmox2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Hmox2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Hmox2.


    Maguire, DP; Turton, JA; et al. Correlation of Histopathology, Urinary Biomarkers, and Gene Expression Responses Following Hexachloro-1:3-Butadiene-induced Acute Nephrotoxicity in Male Hanover Wistar Rats: A 28-day Time Course Study. TOXICOLOGIC PATHOLOGY 41:779-794(2013).
    Lonati, C; Sordi, A; et al. Molecular Changes Induced in Rat Liver by Hemorrhage and Effects of Melanocortin Treatment. ANESTHESIOLOGY 116:692-700(2012).

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