Recombinant Human HMOX2

• Cat.No.: HMOX2-27005TH
• Product Overview: Recombinant full length Human Heme oxygenase 2 with N-terminal proprietary tag; amino acids 1-316, 62kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 1-316 a.a.
• Description: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the heme oxygenase family.Contains 2 HRM (heme regulatory motif) repeats.
• Full Length: Full L.

Gene Information

• Gene Name: HMOX2 heme oxygenase (decycling) 2 [ Homo sapiens ]
• Official Symbol: HMOX2
• Synonyms: HMOX2; heme oxygenase (decycling) 2; heme oxygenase 2; HO 2
• Gene ID: 3163
• mRNA Refseq: NM_001127204
• Protein Refseq: NP_001120676
• MIM: 141251
• Uniprot ID: P30519
• Chromosome Location: 16p13.3
• Pathway: Heme degradation, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Mineral absorption, organism-specific biosystem
• Function: electron carrier activity; heme oxygenase (decyclizing) activity; metal ion binding; oxidoreductase activity; protein binding