ifi27
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  • Official Full Name
  • interferon, alpha-inducible protein 27
  • Background
  • Interferon alpha-inducible protein 27 is a protein that in humans is encoded by the IFI27 gene.
  • Synonyms
  • IFI27; interferon, alpha-inducible protein 27; interferon alpha-inducible protein 27, mitochondrial; FAM14D; P27; 2310061N23Rik; FAM 14D; IFI 27; Interferon alpha induced 11.5 kDa protein; Interferon alpha inducible protein 27; Interferon inducible protein 27; ISG 12; ISG12; ISG12(a) protein; ISG12(a); interferon-stimulated gene 12a protein; interferon alpha-induced 11.5 kDa protein; ISG12A
Cat.#:IFI27-2198RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey IFI27 Protein, His-tagged
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Cat.#:IFI27-5296HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human IFI27 293 Cell Lysate
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Involved Pathway

IFI27 involved in several pathways and played different roles in them. We selected most pathways IFI27 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFI27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
FGF20A; IFITM3; TRIM62; HERC5; HAVCR2; SPRED3; PELI1; SPRED1; FRS2; TRIM26
Immune System
CXADR; RAET1E; CMTM2A; CASPBL; IFI16; TNIP2; TRIM39; FAM49BA; KIF5B; RNF34
Interferon Signaling
IFIT2; EIF4G2; EIF4G2A; USP18; GBP6; TRIM62; TRIM2; IFIT8; HERC5; XAF1
Interferon alpha/beta signaling
IFI6; IFI27; GBP2; IFI35; ISG20; IRF4; XAF1; MX2; IFIT2; IRF9

Protein Function

IFI27 has several biochemical functions, for example, RNA polymerase II activating transcription factor binding, lamin binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by IFI27 itself. We selected most functions IFI27 had, and list some proteins which have the same functions with IFI27. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II activating transcription factor binding
Related Protein TP53BP1; MAD2L2; TBX3; LDB1; BEX1; RB1; POU1F1; SIN3A; NFE2L2; TBX20
Function lamin binding
Related Protein LBR; TMPO; NARF; TOR1AIP1; PKP1; TMEM201; SUN2; SYNE1; PPP4C; BNIP3L
Function molecular_function
Related Protein SETD5; POMZP3; TMEM120A; TBC1D8B; LYPD8; DSCR3; KRTAP5-2; DCAF12L1; FAM209A; HDHD1A

Interacting Protein

IFI27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFI27 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFI27.
TFAP2A; yopM; q5ngf6_fratt; gntT2; sSL2; nifJ; nsr; ezrA; yndJ; q81va8_bacan; mdtB; maeA; glsA1; TFAP2C

IFI27 Related Articles

Malhotra, S; Bustamante, MF; et al. Search for Specific Biomarkers of IFN beta Bioactivity in Patients with Multiple Sclerosis. PLOS ONE 6:-(2011).
Kimoto, O; Sawada, J; et al. Activation of the Interferon Pathway in Peripheral Blood of Patients with Sjogren's Syndrome. JOURNAL OF RHEUMATOLOGY 38:310-316(2011).
Sellebjerg, F; Krakauer, M; et al. Identification of new sensitive biomarkers for the in vivo response to interferon-beta treatment in multiple sclerosis using DNA-array evaluation. EUROPEAN JOURNAL OF NEUROLOGY 16:1291-1298(2009).
Saito, T; Ji, G; et al. Genetic variations in humans associated with differences in the course of hepatitis C. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 317:335-341(2004).

IFI27 Related Gene Family

Cytokines