ifna8
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  • Official Full Name
  • interferon, alpha 8
  • Background
  • Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene.
  • Synonyms
  • IFNA8; interferon, alpha 8; interferon alpha-8; IFN alphaB; interferon alpha type 201; interferon alpha B; Interferon alpha B2; LeIF B; IFN-alpha-8; interferon alpha-B; interferon alpha-B2; IFN-alphaB
Cat.#:IFNA8-1192HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA8 Protein, MYC/DDK-tagged
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Cat.#:IFNA8-321HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA8, His-tagged
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Cat.#:IFNA8-341HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA8, Gly & Pro tagged
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Cat.#:IFNA8-45HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Interferon, Alpha 8
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Cat.#:IFNA8-73CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant cynomolgus IFNA8, Fc tagged
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Cat.#:IFNA8-74CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA8, His tagged
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Cat.#:IFNA8-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA8 cell lysate
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Cat.#:IFNA8-1012HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IFNA8 cell lysate
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Cat.#:IFNA8-1022CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA8 cell lysate
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Cat.#:IFNA8-1035CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IFNA8 cell lysate
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Involved Pathway

IFNA8 involved in several pathways and played different roles in them. We selected most pathways IFNA8 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
OSTN; IL26; PDGFRA; TGFBR1; CXCL8B.3; CD40; CXCR3; TNFSF18; CXCR7; TNFRSF11B
Regulation of autophagy
ATG16L1; ULK1; Ifna15; GABARAPL2; ATG10; IFNA5; PRKAA2; BECN1; ATG12; IFNA16
PIK-Akt signaling pathway
Fgf15; IL6R; PIK3CD; IFNA21; TSC2; GNB3; GNB4; PKN1; ITGA10; BAD
Toll-like receptor signaling pathway
LBP; TLR1LA; IRAK4; IKBKG; MAPK3; AKT3A; PIK3R3B; NFKBIAA; IFNA2; PIK3CA
RIG-I-like receptor signaling pathway
IFNA1; MAPK12B; CASP8; IFNA16; NFKBIAB; FADD; MAP3K7; IL-8; IFNA3; MAPK12A
Cytosolic DNA-sensing pathway
PYCARD; IFNPHI3; CCL4L2; POLR3K; CASP1; MAVS; CCL4L1; POLR2L; IFNA1; IFI202B
Jak-STAT signaling pathway
IL23R; OSM; IFNA7; STAM2; LIF; FHL1B; IFNA10; CRFB2; STAT6; IL20RB
Natural killer cell mediated cytotoxicity
Fasl; TNFRSF10C; KLRC4-KLRK1; SH3BP2; IFNGR1; RAET1L; Ifna15; FCER1G; KIR2DS4; TNFRSF10D
Tuberculosis
TLR2; RAB5C; CORO1A; IL1A; C3; TRADD; CALML5; LAMP1; CARD9; H2-AA
Hepatitis C
EIF3E; IKBKG; BRAF; STAT3; PIK3CD; PPP2CB; CLDN3; OCLN; OAS2; PPP2CA
Hepatitis B
CYCS; FAS; NRAS; ATF4; AKT1; PIK3CG; TICAM2; FADD; PTK2B; IKBKE
Measles
IFNGR2; IFNA14; IFNA13; CD3D; STAT2; IRF3; Cd209g; Ifna11; PIK3R2; AKT2
Influenza A
PIK3R5; STAT2; PRSS2; MAP2K7; MYD88; Fasl; DNAJB1; PIK3CG; PIK3R3; MAPK9
Herpes simplex infection
HNRNPK; IKBKE; H2-AA; IFNG; NXF1; MHC1UEA; FAS; BMA1; TNFRSF1A; STAT2
Autoi
IFNA17; HLA-DOB; IFNA8; IFNA10; IFNA2; GZMB; IFNA6; IFNA4; H2-Q10; IFNA5
ne thyroid disease
IFNA7; Il2; TSHB; IFNA17; HLA-G; IFNA6; HLA-A; IFNA4; CD80; HLA-DRB3

Protein Function

IFNA8 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA8 itself. We selected most functions IFNA8 had, and list some proteins which have the same functions with IFNA8. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein GDF5; CER1; TXLNA; CMTM2; CCL38A.4; IL5; IL37; IL17A/F2; IL24; GDF10
Function cytokine receptor binding
Related Protein IL17A/F2; IL17F; IFNA21; IFNPHI2; IFNA3; IFN-a; IFNA5; IL17A; IL17A/F1; IFNA12
Function type I interferon receptor binding
Related Protein IFNK; IFNPHI4; OSTN; IFNA6; IFNA13; IFNPHI1; GM13288; IFNA21; GM13289; IFNA7

IFNA8 Related Articles

Fujita, M; Scheurer, ME; et al. Role of Type 1 IFNs in Antiglioma Immunosurveillance-Using Mouse Studies to Guide Examination of Novel Prognostic Markers in Humans. CLINICAL CANCER RESEARCH 16:3409-3419(2010).

IFNA8 Related Gene Family

Cytokines