Recombinant Full Length Human IFNA8 Protein, C-Flag-tagged

• Cat.No.: IFNA8-1823HFL
• Product Overview: Recombinant Full Length Human IFNA8 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including B cell activation; lymphocyte activation involved in immune response; and positive regulation of peptidyl-serine phosphorylation of STAT protein. Predicted to act upstream of or within defense response to virus. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 21.8 kDa
• AA Sequence: MALTFYLLVALVVLSYKSFSSLGCD LPQTHSLGNRRALILLAQMRRISPF SCLKDRHDFEFPQEEFDDKQ FQKAQAISVLHEMIQQTFNLFSTKD SSAALDETLLDEFYIELDQQLNDLE SCVMQEVGVIESPLMYEDSI LAVRKYFQRITLYLTEKKYSSCAWE VVRAEIMRSFSLSINLQKRLKSKE TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Gene Information

• Gene Name: IFNA8 interferon alpha 8 [ Homo sapiens (human) ]
• Official Symbol: IFNA8
• Synonyms: IFN-alphaB
• Gene ID: 3445
• mRNA Refseq: NM_002170.4
• Protein Refseq: NP_002161.2
• MIM: 147568
• UniProt ID: P32881