• Official Full Name
  • integrator complex subunit 12
  • Background
  • INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large;subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2;(RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).
  • Synonyms
  • INTS12; integrator complex subunit 12; PHD finger protein 22 , PHF22; hypothetical nuclear factor SBBI22; INT12; SBBI22; PHD finger protein 22; PHF22
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse INTS12 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat INTS12 Protein
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus INTS12 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey INTS12 Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish INTS12
Source (Host):Species:Human
Product nameRecombinant Human INTS12 293 Cell Lysate

Protein Function

INTS12 has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INTS12 itself. We selected most functions INTS12 had, and list some proteins which have the same functions with INTS12. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein CLINT1; EXOC7; PRKAA2; TGFBR1; PAX9; KRTAP3-1; GEMIN8; AP4B1; GLE1; CHMP4C
Function zinc ion binding
Related Protein RNF149; XRN2; ADH6; CBLC; TRIM35-19; HHIP; MSRB2; TLL2; RABGGTB; ADAM25

Interacting Protein

INTS12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INTS12 here. Most of them are supplied by our site. Hope this information will be useful for your research of INTS12.
PPP2R1A; PPP2CB; Ppp2ca; PPP2CA; SNW1; Ppp2r1a; Ints4; RNF169; VWA9; NELFA