isg20
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  • Official Full Name
  • interferon stimulated exonuclease gene 20kDa
  • Background
  • Interferon-stimulated gene 20 kDa protein is a protein that in humans is encoded by the ISG20 gene.
  • Synonyms
  • ISG20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene (20kD); interferon-stimulated gene 20 kDa protein; CD25; HEM45; Estrogen regulated transcript 45 protein; Interferon stimulated gene 20 kDa protein; Promyelocytic leukemia nuclear body associated protein; OTTHUMP00000192918; estrogen-regulated transcript 45 protein; promyelocytic leukemia nuclear body-associated protein ISG20
Cat.#:ISG20-5018HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ISG20 Protein, GST-tagged
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Cat.#:ISG20-28642THTag:His
Source (Host):Species:Human
Product nameRecombinant Human ISG20, His-tagged
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Cat.#:ISG20-2307RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ISG20 Protein, His-tagged
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Cat.#:ISG20-5151HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ISG20 293 Cell Lysate
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Involved Pathway

ISG20 involved in several pathways and played different roles in them. We selected most pathways ISG20 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ISG20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
RASGRP4; PEA15A; FGF10B; IFIT2; IFITM3; DUSP7; TRIM45; EIF4A1; CSF2RB; CASPBL
Immune System
UBE2F; AP1S1; KPNA3; CASPB; LRRC41; RCA2.1; MGC174857; KIF22; MYO1C; DEFB4B
Interferon Signaling
IFITM3; IRF2; IFI6; IFIT11; TRIM31; OASL; GBP5; GBP1; TRIM68; SAMHD1
Interferon alpha/beta signaling
IFIT2; IFITM2; BST2; IFI6; IFI35; MX2; ISG20; GBP2; IRF2; IRF6

Protein Function

ISG20 has several biochemical functions, for example, 3-5-exoribonuclease activity, U1 snRNA binding, U2 snRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ISG20 itself. We selected most functions ISG20 had, and list some proteins which have the same functions with ISG20. You can find most of the proteins on our site.
Function
Related Protein
Function 3-5-exoribonuclease activity
Related Protein TOE1; SMFN; ERI2; EXOSC2; CNOT7; PAN2; EXOSC4; DIS3L; ERI1; PNPT1
Function U1 snRNA binding
Related Protein SNRPA; SNRNP70; PRPF8; ISG20
Function U2 snRNA binding
Related Protein PRPF8; TROVE2; SNRPA1; ISG20
Function U3 snoRNA binding
Related Protein DIEXF; ISG20; NHP2L1
Function exonuclease activity
Related Protein WRN; REXO1L1; REXO1; ISG20; XRN1; LOC81691; FEN1; CNOT6L; TDP1; CNOT6
Function exoribonuclease II activity
Related Protein ISG20
Function metal ion binding
Related Protein LMO4B; KDM7AB; ZIC2; PFKL; ERCC2; RSAD2; SMG6; TRIM46B; SCD5; ZNF45
Function single-stranded DNA 3-5 exodeoxyribonuclease activity
Related Protein ISG20; MEIOB; DEM1

ISG20 Related Gene Family

Cytokines