|Official Full Name||integrin, alpha 9|
|Background||This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]|
|Synonyms||ITGA9; integrin, alpha 9; RLC; ITGA4L; ALPHA-RLC; integrin alpha-9; integrin alpha-RLC;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ITGA9 involved in several pathways and played different roles in them. We selected most pathways ITGA9 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|PIK-Akt signaling pathway||AKT2; PPP2CB; IKBKB; ITGA4; PIK3CD; PIK3R5; COL6A6; TCL1A; PPP2R1A; IFNB1|
|Focal adhesion||PARVB; RAC2; DOCK1; VAV1; COL6A4; ITGA11A; VAV2; LAMA5; RAF1A; COL27A1B|
|ECM-receptor interaction||TNR; COL1A1A; TNW; COL4A6; SPP1; THBS4B; ITGB5; GP6; LAMA4; LAMB2|
|Cell adhesion molecules (CAMs)||CLDN3; CADM3; CD8B1; CLDN4; H2-AA; NLGN1; BLA; H2-AB1; MADCAM1; HLA-F|
|Regulation of actin cytoskeleton||FGF11A; CD14; PTK2AA; APC2; PFN1; CYFIP1; RHOA; MYL2; VCL; ITGB1|
|Hypertrophic cardiomyopathy (HCM)||ITGA8; TGFB2; CACNG4; MYL2; ITGB3; SGCG; CACNA2D2; ITGA4; RYR2; CACNG1|
|Arrhythmogenic right ventricular cardiomyopathy (ARVC)||SGCD; CDH2; SGCA; CACNB2; CACNB1; RYR2; ITGA1; CTNNA3; ACTN1; CTNNA1|
|Dilated cardiomyopathy||IGF1; TTN; ITGB5; ITGA8; TGFB3; TPM4; TPM1; MYL2; GNAS; ITGA2B|
ITGA9 has several biochemical functions, for example, collagen binding, laminin binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA9 itself. We selected most functions ITGA9 had, and list some proteins which have the same functions with ITGA9. You can find most of the proteins on our site.
|collagen binding||ITGA1; Itga10&Itgb1; ITGA10; CTSB; VWF; PODN; SMAD7; DCN; CD44; PDGFA|
|laminin binding||BCAM; LYPD3; AGRN; CTSS; LRRC15; NCL; ECM1; ITGA7; NID1; RPSA|
|metal ion binding||ENOPH1; MAP3K3; TIMP2; SCD5; SMG6; SDHC; SMAD7; CPEB1; DGCR8; ZNF843|
ITGA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA9.