junb
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  • Official Full Name
  • jun B proto-oncogene
  • Background
  • The JunB transcrIPPtion factor, also known as JunB proto-oncogene, JunB oncogene, transcrIPPtion factor JunB, and transforming protein JunB, is a basic region leucine zIPPer DNA-binding protein, and a member of the Jun family of proteins, which also inclu
  • Synonyms
  • JUNB; jun B proto-oncogene; transcription factor jun-B; activator protein 1; AP-1
Cat.#:JUNB-218HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUNB, GST-tagged
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Cat.#:JUNB-8439MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUNB Protein
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Cat.#:JUNB-3147RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUNB Protein
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Cat.#:JUNB-2336RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey JUNB Protein, His-tagged
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Cat.#:JUNB-886HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human JUNB cell lysate
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Involved Pathway

JUNB involved in several pathways and played different roles in them. We selected most pathways JUNB participated on our site, such as ATF-2 transcription factor network, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUNB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ATF-2 transcription factor network
GADD45A; JUND; POU2F1; DUSP10; CBFB; CDK4; CSRP2; KAT5; MAPK14; RUVBL2
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
POU2F1; CDK4; EGR3; IRF4; CTLA4; JUNB; BATF3; IKZF1; EGR4; EGR1
Calcium signaling in the CD4+ TCR pathway
POU2F1; FKBP1A; CHP; BATF3; RCAN1; RCAN2; CSF2; JUNB; AKAP5
Corticotropin-releasing hormone
CYP11B1; CYP11A1; CASP12; IVL; KRT14; JUND; KRT1; CYP21A2; JUNB; CRHBP
Downstream signaling in naive CD8+ T cells
EGR1; EGR4; JUNB; EOMES
Gene Expression
HIPK1; HNRNPA0B; ZNF302; DCP2; TRMT11; NR2F6B; TYW5; NKX2; RRP8; SMARCA5
Generic Transcription Pathway
ZNF100; COX8A; ZNF493; ZNF680; RXRBB; ZNF705A; ZNF213; TEAD1A; NR4A2B; ZNF256
IL6-mediated signaling events
CRP; LMO4; PIAS3; JUNB

Protein Function

JUNB has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, RNA polymerase II transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUNB itself. We selected most functions JUNB had, and list some proteins which have the same functions with JUNB. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP184; PCXB; MBD1B; OASL; ZFP292; PMS2; HIST1H4C; HOXA4; IRX7; SIM1B
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SNAI3; DPF2; AGO1; ZNF114; POU2F2; TFAP2A; MIXL1; NKX6; NFYC; HOXA5
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein OVOL3; ARX; SOX9B; TP53; FOXQ2; ZNF446; ZSCAN5A; FOXA3; FOXQ1; MEF2C
Function protein binding
Related Protein CCL28; CARM1; UPF1; KCNS2; MIS18BP1; MYOT; DIRAS3; AK8; NDUFAF1; FUBP1
Function transcription coactivator activity
Related Protein MED12; SUPT7L; PRPF6; JMY; RIPK3; YAF2; KMT2E; BIRC2; ATXN7L3; SMARCA4
Function transcription corepressor activity
Related Protein PAWR; SOD3; UBP1; ZNF274; E2F8; CBFA2T3; SSX2; ZNF136; ALX1; TBL1X
Function transcription factor binding
Related Protein MAFB; RNF222; GTF2B; ESRRB; TAF7L; HTT; GTF2A2; CEBPG; DIP2C; PPP1R13B
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein POU1F1; NKX2; TP53; PITX1; LEF1; KLF4; SRF; PLAG1; SPI1; ONECUT2

Interacting Protein

JUNB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUNB here. Most of them are supplied by our site. Hope this information will be useful for your research of JUNB.
FOS; BATF; FOS; ATF2; FOSL2

JUNB Related Articles

Atsaves, V; Lekakis, L; et al. The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK plus anaplastic large cell lymphoma. BRITISH JOURNAL OF HAEMATOLOGY 167:514-523(2014).
Perdomo, MF; Hosia, W; et al. Human serum protein enhances HIV-1 replication and up-regulates the transcription factor AP-1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:17639-17644(2012).