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KDM3A

  • Official Full Name

    lysine (K)-specific demethylase 3A

  • Overview

    This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. Alternative splicing results in multiple transcript variants.
  • Synonyms

    KDM3A; lysine (K)-specific demethylase 3A; TSGA; JMJD1; JHDM2A; JHMD2A; JMJD1A; KIAA0742; DKFZp686A24246; DKFZp686P07111; lysine-specific demethylase 3A; OTTHUMP00000160707; OTTHUMP00000203309; testis-specific protein A; jumonji domain containing 1; jumonji domain containing 1A; jumonji domain-containing protein 1A; jumonji C domain-containing histone demethylase 2A; jmjC domain-containing histone demethylation protein 2A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Sf9 Insect Cell
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KDM3A-48H Active Recombinant Human KDM3A, FLAG-tagged Sf9 Insect Cell Flag
Human KDM3A-301H Recombinant Human KDM3A, GST-tagged E.coli GST N-term-358aa
Human KDM3A-4997HCL Recombinant Human KDM3A 293 Cell Lysate HEK293 N/A
Mouse KDM3A-8589M Recombinant Mouse KDM3A Protein Mammalian Cell His
Mouse KDM3A-4778M Recombinant Mouse KDM3A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Kdm3a-255M Recombinant Mouse Kdm3a Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse KDM3A-4778M-B Recombinant Mouse KDM3A Protein Pre-coupled Magnetic Beads HEK293
Rat KDM3A-3236R Recombinant Rat KDM3A Protein Mammalian Cell His
Rat KDM3A-2892R Recombinant Rat KDM3A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat KDM3A-2892R-B Recombinant Rat KDM3A Protein Pre-coupled Magnetic Beads HEK293
Chicken KDM3A-2106C Recombinant Chicken KDM3A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KDM3A Related Articles
  • KDM3A Related Research Area

KDM3A involved in several pathways and played different roles in them. We selected most pathways KDM3A participated on our site, such as Chromatin modifying enzymes, Chromatin organization, Coregulation of Androgen receptor activity, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesACTL6A;KDM2AA;HIST2H3C;KAT5;KDM5D;ING5B;KDM5BB;MBD3B;EPC1
Chromatin organizationATF7IP;ING5B;PHF15;KDM1A;CAPNS2;TADA3;KDM2AA;DNMT3A;PBRM1
Coregulation of Androgen receptor activityNRIP1;CTDSP1;PIAS3;PATZ1;PA2G4;SVIL;KDM3A;SNURF;ZMIZ1
HDMs demethylate histonesKDM4C;KDM5A;KDM5B;KDM2B;JMJD6;KDM6AL;KDM3A;ARID5B;KDM1B

KDM3A has several biochemical functions, for example, androgen receptor binding, core promoter binding, dioxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KDM3A itself. We selected most functions KDM3A had, and list some proteins which have the same functions with KDM3A. You can find most of the proteins on our site.

Function Related Protein
androgen receptor bindingFOXP1;RNF14;SMARCA4;CALR;FOXH1;NCOA4;DAXX;RAN;PRKCBB
core promoter bindingDHX36;E2F1;MYBBP1A;HNRNPU;E2F2;PYDC3;INSM1B;KDM3A;TFAP2C
dioxygenase activityALOX12E;BCO2L;KDM4C;ALKBH6;KDM3A;ALOX8;KDM4B;KDM5BB;ADOA
iron ion bindingCYP2D26;FA2H;CYP11B1;Agmo;CYP2F2;CYP4F3;CYP2X9;CYP8B2;ALOX15
transcription factor activity, sequence-specific DNA bindingRXRAB;TAF4B;GTF2H3;GATA1A;CBFB;SOX6;POU4F2;RFXAP;FOXA2
transcription regulatory region sequence-specific DNA bindingMEF2CA;EPAS1B;GATA3;FOXJ1;TBX18;MEF2AA;NFKB1;ATF3;NFE2L2B

KDM3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM3A here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM3A.

TCEAL1; RIPK2; Chmp6; POLR2F; CBX2; Chmp3; Dut

Guo, XQ; Tian, ZT; et al. Regulation of histone demethylase KDM6B by hypoxia-inducible factor-2 alpha. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47:106-113(2015).
Parrish, JK; Sechler, M; et al. The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma. ONCOGENE 34:257-262(2015).
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