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Official Full Name Kell blood group
Background This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains s
Synonyms KEL; Kell blood group; kell blood group glycoprotein homolog; CD238; CD238 antigen; ECE3; Kell blood group glycoprotein; Kell blood group metallo endopeptidase; Kell blood group metalloendopeptidase; KELL NULL; Kell protein; KELL_HUMAN; OTTMUSP00000032452; Kel blood group protein; Kell blood group, metallo-endopeptidase
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Insect cells
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Kel-018M Recombinant Mouse Kel Protein, His-tagged Insect cells His
    Human KEL-1836H Recombinant Human KEL protein, His & T7-tagged E.coli His/T7
    Human KEL-26282TH Recombinant Human KEL Wheat Germ N/A
    Human KEL-4990HCL Recombinant Human KEL 293 Cell Lysate HEK293 N/A
    Mouse Kel-1837M Recombinant Mouse Kel protein, His & T7-tagged E.coli His/T7
    Mouse Kel-1976M Recombinant Mouse Kell Blood Group, His-tagged NS0 His
    Mouse KEL-8604M Recombinant Mouse KEL Protein Mammalian Cell His
    Rat Kel-1838R Recombinant Rat Kel protein, His & T7-tagged E.coli His/T7

    KEL involved in several pathways and played different roles in them. We selected most pathways KEL participated on our site, such as Class A/1 (Rhodopsin-like receptors), GPCR ligand binding, Peptide ligand-binding receptors, which may be useful for your reference. Also, other proteins which involved in the same pathway with KEL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) LPAR5A; NTS; CNR2; S1PR5B; QRFPR; GPR65; EDNRB; TAC1; RLN2; ADRA2C
    GPCR ligand binding PYY; PNOCB; NMS; ACKR4; FFAR3; FPR-RS4; INSL5; EDNRAB; RAMP1; GPR120
    Peptide ligand-binding receptors SSTR1; RXFP2; RLN2; PRLH; SSTR5; EDN3; PENK; CXCR7B; HEBP1; RLN3A
    Signal Transduction LGR5; MYO9B; ALDH8A1; RBP2A; LRP10; IFT88; BCL9L; UCHL5; RGS10; SOUL3
    Signaling by GPCR RGS7; GAL; NMBB; RGS11; KISS1; HCAR1-2; INSL5; PTH2; ARHGEF3; PROK2

    KEL has several biochemical functions, for example, metal ion binding, metalloendopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KEL itself. We selected most functions KEL had, and list some proteins which have the same functions with KEL. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding ZNF791; WT1A; QTRT1; ZBTB24; ZDHHC20A; DOHH; PRKCZ; MAT2AL; PDP1; B4GALT5
    metalloendopeptidase activity MEP1A.2; ADAM32; THOP1; MIPEP; MMP30; ADAMTS15; ASTL; YBEY; MEP1A; MMP19
    protein binding RAB32; FAM90A1; NOP2; TMEM123; SPI1; RAB37; ABCG2; FHIT; RIPK2; FAM58A

    KEL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KEL here. Most of them are supplied by our site. Hope this information will be useful for your research of KEL.


    Boturao-Neto, E; Yamamoto, M; et al. Molecular Basis of KELnull Phenotype in Brazilians. TRANSFUSION MEDICINE AND HEMOTHERAPY 42:52-58(2015).
    Meyer, S; Vollmert, C; et al. High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles. TRANSFUSION 54:3198-3207(2014).

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