Active Recombinant Mouse Kell Blood Group, His-tagged
Cat.No. : | Kel-1976M |
Product Overview : | RecombinantMouse Kel protein was expressed in Murine myeloma cell line. Phe50-Trp713,with an N-terminal 7-His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Kel-1976M |
Description : | Kel islinked through a single disulfide bond to XK, a putative membranetransporter. The two proteins constitute the Kel bloodgroup antigens. Kel is a zinc endopeptidase of the neprilysin(NEP) family which also includes endothelin converting enzymes (ECE-1 and ECE-2),PEX, XCE, DINE and several NEP-like proteins. It has been shown to cleave bigendothelin-3 (ET-3) at Trp21-Ile22, yielding ET-3, and to a much lesserextent, big ET-1 and big ET-2 at Trp21-Val22, yielding ET-1 and ET-2. Severaldifferent molecular defects cause the Kel null phenotype,which has no obvious clinical outcome. |
Source : | Mammalian cells |
Form : | Supplied as a 0.2 umfiltered solution in Tris, NaCl and ZnCl2. |
N-terminalSequence : | His |
MolecularWeight : | 76 kDa |
Activity : | Measuredby its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK (Dnp)-OH.The specific activity is > 0.2 pmoles/min/μg, as measured under thedescribed conditions. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 106 kDa,reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freezethawcycles. 6months from date of receipt, -20 to -70°C as supplied. 3 months, -20 to -70°Cunder sterile conditions after opening. |
Gene Name : | Kel Kell blood group [ Musmusculus ] |
Official Symbol : | Kel |
Synonyms : | Kel; Kell bloodgroup; Ece3;CD238; kell blood group glycoprotein homolog; Kell protein; Kel blood groupprotein; Kell blood group, metallo-endopeptidase |
Gene ID : | 23925 |
mRNA Refseq : | NM_032540 |
Protein Refseq : | NP_115929 |
UniProt ID : | Q9EQF2 |
Chromosome Location : | 6 |
Function : | endopeptidase activity;hydrolase activity; metal ion binding; metalloendopeptidase activity;metallopeptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
KEL-079H | Recombinant Human KEL Protein, His-tagged | +Inquiry |
Kel-4791M | Recombinant Mouse Kel Protein, His (Fc)-Avi-tagged | +Inquiry |
Kel-018M | Recombinant Mouse Kel Protein, His-tagged | +Inquiry |
KEL-8604M | Recombinant Mouse KEL Protein | +Inquiry |
KEL-1836H | Recombinant Human KEL protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
KEL-4990HCL | Recombinant Human KEL 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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