KIF2A
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Official Full Name
kinesin heavy chain member 2A
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Overview
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
KIF2A; kinesin heavy chain member 2A; KIF2, kinesin heavy chain member 2; kinesin-like protein KIF2A; HK2; kinesin-2; Kinesin, heavy chain, 2; KIF2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- E.coli
- HEK293
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | KIF2A-370H | Recombinant Human KIF2A, GST-tagged | E.coli | GST | C-term-352aa | |
Human | KIF2A-4947HCL | Recombinant Human KIF2A 293 Cell Lysate | HEK293 | N/A | ||
Mouse | KIF2A-8640M | Recombinant Mouse KIF2A Protein | Mammalian Cell | His | ||
Mouse | KIF2A-4815M-B | Recombinant Mouse KIF2A Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | KIF2A-4815M | Recombinant Mouse KIF2A Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | KIF2A-2405R | Recombinant Rhesus monkey KIF2A Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | KIF2A-2226R | Recombinant Rhesus Macaque KIF2A Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | KIF2A-2226R-B | Recombinant Rhesus Macaque KIF2A Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chicken | KIF2A-3371C | Recombinant Chicken KIF2A | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- KIF2A Related Gene Family
KIF2A involved in several pathways and played different roles in them. We selected most pathways KIF2A participated on our site, such as Adaptive Immune System, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Adaptive Immune System | GAN;SEC23A;HECTD3;IGKV1-5;CD300E;CD200R2;SIGLEC7;CDKN1B;CD300LF |
Cell Cycle | MCM6L;STAG2;BRE;BABAM1;SET;CENPK;DIDO1;CDC14B;PTTG2 |
Cell Cycle, Mitotic | MCPH1;CLASP1A;CENPP;CDT1;CENPK;DPF1;CEP135;ZWINT;TMPO |
Factors involved in megakaryocyte development and platelet production | MYB;DOCK7;AKAP1;DOCK2;KIF20A;DOCK11;EHD1;HBB-Y;IRF1B |
Hemostasis | AKAP1;RAPGEF3;SLC3A2A;TRPC3;MFN2;CD84;GATA2A;ANGPT2A;WDR1 |
Immune System | ASB9;UNC93B1;CASPBL;AGER;FBXO27;IFIT3;ASB7;UBE2E3;FBXO44 |
Kinesins | KIFC1;KIF22;KIF5A;KIF18A;KIF2A;KIF4A;KIF3B;KIF4;RACGAP1 |
M Phase | MASTL;SPC24;SETB;NEK9;NEK6;SET;NEK7;INCENP;CENPO |
KIF2A has several biochemical functions, for example, ATP binding, ATPase activity, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF2A itself. We selected most functions KIF2A had, and list some proteins which have the same functions with KIF2A. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | AGK;EHD2;HIPK1;PDPK1B;P2RX3;ABCC9;ATP1A1B;UBE2U;CSNK1G2 |
ATPase activity | ABCA1B;PSMD6;KIFC3;WRNIP1;MYH9;TOR1A;ATAD1;ABCD3B;KIF25 |
microtubule binding | SBDS;KIF21A;NUMA1;PAFAH1B1A;WHAMM;TPPP;KIF3B;MID2;DPYSL5A |
microtubule motor activity | SMC3;DNAH6;DYNC1H1;KLC1;DYNLRB2;KIFC3;KIF14;KIF4A;DNAH14 |
motor activity | MYH7B;MYL3;MYO5C;MYO1G;MYH6;SMYHC3;DNAI1;MYO1C;MYH9 |
protein binding | ZNF436;TACR3;PNMA2;KRT14;HEATR5B;DPH1;IL13;KLHL38;CSNK2A2 |
KIF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF2A.
LARP1B; FAM13C; MRPL53; MYB; pi3p; ssrna_ug; EIF3F; KIAA0556; EXOC3; LTN1; UBR5; UBL4A
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