|Official Full Name||Kruppel-like factor 10|
|Background||This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]|
|Synonyms||KLF10; Kruppel-like factor 10; EGRA; TIEG; TIEG1; EGR-alpha; Krueppel-like factor 10; early growth response-alpha; zinc finger transcription factor TIEG; TGFB-inducible early growth response protein 1; transforming growth factor-beta-inducible early growth response protein 1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLF10 involved in several pathways and played different roles in them. We selected most pathways KLF10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLF10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
KLF10 has several biochemical functions, for example, core promoter sequence-specific DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF10 itself. We selected most functions KLF10 had, and list some proteins which have the same functions with KLF10. You can find most of the proteins on our site.
|core promoter sequence-specific DNA binding||GATA3; THRAP3; CREM; NRF1; SOX4; PROX1; NRIP1; ZFHX3; ZNF750; SOX1|
|metal ion binding||TSHZ3; DMPK; PTGS1; DMRTA1; ZNF280C; ZNF763; BTK; FCNA; PRKCBA; PRDM1|
|protein binding||RUFY4; TSSK3; TSPAN2; TRPC3; HUWE1; LBR; ELF2; ALOX5; SELE; CLK3|
|transcription factor activity, sequence-specific DNA binding||ZFP184; TEAD3B; SP140; RAI1; TP63; MGAA; GLI3; TARDBP; IKZF2; CSRNP2|
KLF10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF10 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF10.
SP1; CDK6; TULP3; TFAP2A; RPL14; CRIP2; BOP1; SF3B3; ogl; LRRC75A-AS1; PIGC; LENG1; ZNF512B; TNS1; foxp3_human_gene; tgfb1_human_gene; MYC