|Official Full Name||kallikrein-related peptidase 15|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]|
|Synonyms||KLK15; kallikrein-related peptidase 15; ACO; HSRNASPH; kallikrein-15; prostinogen; ACO protease; kallikrein-like serine protease;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLK15 involved in several pathways and played different roles in them. We selected most pathways KLK15 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
KLK15 has several biochemical functions, for example, protein binding, serine-type endopeptidase activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK15 itself. We selected most functions KLK15 had, and list some proteins which have the same functions with KLK15. You can find most of the proteins on our site.
|protein binding||SEPT11; NLK; ALOX5AP; ABHD16A; EGLN2; TUBG1; ANTXR1; NRP1B; ORC1L; GBP2|
|serine-type endopeptidase activity||PCSK9; TMPRSS11B; CTSH; ST14A; ELA2; PRSS59.1; PRSS45; KLK1B16; PRSS27; TMPRSS3|
|serine-type peptidase activity||TMPRSS11E; FAP; GZMC; MCPT9; TMPRSS4A; ELA2L; DPP10; PRSS52; ENDOU; TMPRSS4B|
KLK15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK15 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK15.