kntc1
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  • Official Full Name
  • kinetochore associated 1
  • Background
  • This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein.
  • Synonyms
  • KNTC1; kinetochore associated 1; kinetochore-associated protein 1; KIAA0166; ROD; rough deal homolog (Drosophila); HsROD; Rough Deal homolog, centromere/kinetochore protein; hRod; OTTHUMP00000236760
Cat.#:KNTC1-4900HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KNTC1 Protein, GST-tagged
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Cat.#:KNTC1-8796MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KNTC1 Protein
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Involved Pathway

KNTC1 involved in several pathways and played different roles in them. We selected most pathways KNTC1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with KNTC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
RAD9; NUP50; LEMD3; CDK6; CSNK1D; DNA2; GSK3AA; GADD45B; DYNC1H1; CEP135
Cell Cycle, Mitotic
SETA; DCTN2; LIN9; MLF1IP; DCTN3; GINS1; CKS1B; NUPL2; CSNK2A2; NUDC
M Phase
MASTL; NDEL1; GORASP2; SGOL2; WAPAL; CTDNEP1; CENPI; ZW10; NIPBLB; CDCA8
Mitotic Anaphase
NUF2; ANKLE2; DSN1; SKA2; PDS5A; KNTC1; NDEL1A; PMF1; CENPO; CENPP
Mitotic Metaphase and Anaphase
NUF2; CENPN; SPC25; MLF1IP; SGOL1; NDC80; PMF1; VRK2; DSN1; SKA2
Mitotic Prometaphase
CLIP1; SKA2; CDCA8; SMC4; ZWILCH; NCAPG; CENPO; CENPI; CENPP; CDCA5
RHO GTPase Effectors
ACTR2B; CIT; KNTC1; NDEL1B; SPC24; CCDC99; NOXA1; NOXO1; ZW10; KIF14
RHO GTPases Activate Formins
CLIP1; SPDL1; NUF2; FMNL2; MKL1; MIS12; AHCTF1; NDEL1B; NDEL1A; RANGAP1B

Protein Function

KNTC1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by KNTC1 itself. We selected most functions KNTC1 had, and list some proteins which have the same functions with KNTC1. You can find most of the proteins on our site.
Function
Related Protein
Function molecular_function
Related Protein FITM1; CUEDC1A; GAGE2B; TLK1; WNK2; D19WSU162E; VMO1; CACHD1; GM10395; PCNXL2

Interacting Protein

KNTC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KNTC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KNTC1.
Ywhah; Iqcb1

KNTC1 Related Articles

Li, BC; Choulet, F; et al. Wheat centromeric retrotransposons: the new ones take a major role in centromeric structure. PLANT JOURNAL 73:952-965(2013).
Huang, X; Wang, HL; et al. DYNLT3 Is Required for Chromosome Alignment During Mouse Oocyte Meiotic Maturation. REPRODUCTIVE SCIENCES 18:983-989(2011).