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KNTC1

Official Full Name

kinetochore associated 1
Overview

This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein.
Synonyms

KNTC1; kinetochore associated 1; kinetochore-associated protein 1; KIAA0166; ROD; rough deal homolog (Drosophila); HsROD; Rough Deal homolog, centromere/kinetochore protein; hRod; OTTHUMP00000236760;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	KNTC1-4900H	Recombinant Human KNTC1 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Mouse	KNTC1-8796M	Recombinant Mouse KNTC1 Protein	Mammalian Cell	His	Inquiry
Mouse	KNTC1-4894M-B	Recombinant Mouse KNTC1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	KNTC1-4894M	Recombinant Mouse KNTC1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein
KNTC1 Related Articles

KNTC1 involved in several pathways and played different roles in them. We selected most pathways KNTC1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with KNTC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	ORC2L;B9D2;CDC16;MSH5;RAD1;RBBP8;GADD45BA;NEK7;CCNA1
Cell Cycle, Mitotic	LIN37;FGFR1OP;CEP152;TUBG2;CENPC1;CEP70;SMC2;SETB;ODF2B
M Phase	ARPP19A;NUDC;STAG2;NCAPD3;AHCTF1;NUF2;PANE1;SKA2;PMF1
Mitotic Anaphase	SPDL1;CDCA8;MIS12;PMF1;ZWILCH;SGOL1;DSN1;ERCC6L;CENPC1
Mitotic Metaphase and Anaphase	CENPH;SPC25;CLIP1;SPDL1;WAPAL;CCDC99;CENPK;ITGB3BP;LEMD3
Mitotic Prometaphase	ZWINT;ZWILCH;PDS5A;CENPQ;INCENP;CDCA8;PDS5B;SMC2;SPC25
RHO GTPase Effectors	NOXO1;PRC1B;NCKIPSD;ABI2;SGOL2;MKL1B;WIPF2;ACTR2B;CIT
RHO GTPases Activate Formins	RANGAP1B;FMNL2;AHCTF1;DIAPH1;SKA1;KNTC1;MKL1B;SGOL2;ZWILCH

KNTC1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by KNTC1 itself. We selected most functions KNTC1 had, and list some proteins which have the same functions with KNTC1. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	FAM167AB;LRTM2;NMBB;HSCB;COX16;PITPNAA;ECRG4A;GID8A;GM8898

KNTC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KNTC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KNTC1.

Ywhah; Iqcb1

Li, BC; Choulet, F; et al. Wheat centromeric retrotransposons: the new ones take a major role in centromeric structure. PLANT JOURNAL 73:952-965(2013).

Huang, X; Wang, HL; et al. DYNLT3 Is Required for Chromosome Alignment During Mouse Oocyte Meiotic Maturation. REPRODUCTIVE SCIENCES 18:983-989(2011).