|Official Full Name||LATS, large tumor suppressor, homolog 1|
|Background||LATS1 (Large tumor suppressor 1) is a putative serine/threonine kinase that belongs to the NDR family. It is a tumor suppressor that plays a critical role in the maintenance of ploidy. LATS1 localizes to the centrosome and the mitotic spindle and controls|
|Synonyms||LATS1; LATS, large tumor suppressor, homolog 1 (Drosophila); LATS (large tumor suppressor, Drosophila) homolog 1; serine/threonine-protein kinase LATS1; WARTS; h-warts; WARTS protein kinase; large tumor suppressor homolog 1; wts|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
LATS1 involved in several pathways and played different roles in them. We selected most pathways LATS1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with LATS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Hippo signaling pathway||GDF5; WWC1; DVL3; NF2; YAP1; FZD3; WNT6; SAV1; FZD1; WNT5A|
LATS1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by LATS1 itself. We selected most functions LATS1 had, and list some proteins which have the same functions with LATS1. You can find most of the proteins on our site.
|ATP binding||NRBP2; KCNJ11; NMNAT1; ACVR2AA; STK32B; EPHB3; ADCK3; WARS; MVD; CENPE|
|magnesium ion binding||TSSK4; CIB4; ADPRH; HPGDS; ATP10A; PGM3; CIB3; FOXK2; IRAK3; OPA1|
|protein binding||KIT; CLCNKB; COL1A2; NAT8B; CALM3; VDAC2; SUV39H1; LRCH3; EFCAB11; GLI2|
|protein kinase binding||FAM83A; CENPJ; CDKN2B; USP37; MAVS; EEF2; PRKAG2; CAV1; KIF11; CADPS|
|protein serine/threonine kinase activity||DCLK3; MAP3K11; BMPR1AB; CAMK1DA; STRC; SRPK1B; CLK3; MAP3K14; MAPK4; SRPK1A|
LATS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LATS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LATS1.
YAP1; MOB1B; MOB1A