lhx5
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  • Official Full Name
  • LIM homeobox 5
  • Background
  • This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice.
  • Synonyms
  • LHX5; LIM homeobox 5; LIM/homeobox protein Lhx5; LHX 5; LHX5_HUMAN; LIM homeobox protein 5; MGC129689
Cat.#:LHX5-572HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LHX5, GST-tagged
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Cat.#:LHX5-9089MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LHX5 Protein
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Cat.#:LHX5-3405RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LHX5 Protein
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Cat.#:LHX5-8819ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish LHX5
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Involved Pathway

LHX5 involved in several pathways and played different roles in them. We selected most pathways LHX5 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells
MAPK1; GRB2; ZIC3; WNT9B; ID2; ID3; FGFR4; INHBE; MAPK12; FZD8

Protein Function

LHX5 has several biochemical functions, for example, sequence-specific DNA binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHX5 itself. We selected most functions LHX5 had, and list some proteins which have the same functions with LHX5. You can find most of the proteins on our site.
Function
Related Protein
Function sequence-specific DNA binding
Related Protein DBX1B; IRX3B; ATF6B; FOXI3A; POU3F2A; IRX2A; NR1D4A; NFE2L2A; FOXN2B; TRP63
Function zinc ion binding
Related Protein RNF19B; PRKCA; NEIL1; ANAPC11; RNF144AB; MYLIP; PGLYRP1; MMP9; ING5; ZDHHC15B

LHX5 Related Articles

Mastick, GS; Andrews, GL; et al. Pax6 regulates the identity of embryonic diencephalic neurons. MOLECULAR AND CELLULAR NEUROSCIENCE 17:190-207(2001).