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LHX5

  • Official Full Name

    LIM homeobox 5

  • Overview

    This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice.
  • Synonyms

    LHX5; LIM homeobox 5; LIM/homeobox protein Lhx5; LHX 5; LHX5_HUMAN; LIM homeobox protein 5; MGC129689;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LHX5-572H Recombinant Human LHX5, GST-tagged E.coli GST 260-402aa
Mouse LHX5-9089M Recombinant Mouse LHX5 Protein Mammalian Cell His
Mouse LHX5-5075M Recombinant Mouse LHX5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse LHX5-5075M-B Recombinant Mouse LHX5 Protein Pre-coupled Magnetic Beads HEK293
Rat LHX5-3405R Recombinant Rat LHX5 Protein Mammalian Cell His
Rat LHX5-3061R Recombinant Rat LHX5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat LHX5-3061R-B Recombinant Rat LHX5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LHX5-8819Z Recombinant Zebrafish LHX5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • LHX5 Related Articles
  • LHX5 Related Research Area

LHX5 involved in several pathways and played different roles in them. We selected most pathways LHX5 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with LHX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Signaling pathways regulating pluripotency of stem cellsMAPK12;FGFR4;FGFR1;ACVR1;PCGF3;ID4;HESX1;MAP2K2;HOXB1

LHX5 has several biochemical functions, for example, sequence-specific DNA binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LHX5 itself. We selected most functions LHX5 had, and list some proteins which have the same functions with LHX5. You can find most of the proteins on our site.

Function Related Protein
sequence-specific DNA bindingBHLHE22;PRDM5;RXRGB;BCL11B;HOXB4A;DMRT3A;NR5A5;HOXA13;NOTCH1
zinc ion bindingRNF212;RNF39;MMP30;PHF14;SP110;XIRP2;ADH1;JUB;ZFR

LHX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LHX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of LHX5.

Mastick, GS; Andrews, GL; et al. Pax6 regulates the identity of embryonic diencephalic neurons. MOLECULAR AND CELLULAR NEUROSCIENCE 17:190-207(2001).
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