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LOR

Official Full Name

loricrin
Overview

This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkels syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008]
Synonyms

LOR; loricrin;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|GST
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	LOR-270H	Recombinant Human LOR	Mammalian Cell	His		Inquiry
Human	LOR-7897H	Recombinant Human LOR protein, His & GST-tagged	E.coli	His/GST	Ser210~Val295 (Accession # P23490)	Inquiry
Human	LOR-28934TH	Recombinant Human LOR	Wheat Germ	N/A	316 amino acids	Inquiry
Human	LOR-1027HCL	Recombinant Human LOR cell lysate		N/A		Inquiry
Human	LOR-3374H	Recombinant Human LOR Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	LOR-5957HF	Recombinant Full Length Human LOR Protein, GST-tagged	In Vitro Cell Free System	GST	316 amino acids	Inquiry
Human	LOR-4735H	Recombinant Human LOR Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	LOR-287HF	Recombinant Full Length Human LOR Protein	In Vitro Cell Free System		316 amino acids	Inquiry
Human	LOR-3374H-B	Recombinant Human LOR Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	LOR-3308H	Recombinant Human LOR protein, His-tagged	E.coli	His	Ser210~Lys312	Inquiry
Mouse	LOR-9183M	Recombinant Mouse LOR Protein	Mammalian Cell	His		Inquiry
Mouse	LOR-5129M	Recombinant Mouse LOR Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	LOR-5129M-B	Recombinant Mouse LOR Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
LOR Related Articles

LOR involved in several pathways and played different roles in them. We selected most pathways LOR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LOR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

LOR has several biochemical functions, for example, protein binding, protein binding, bridging, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by LOR itself. We selected most functions LOR had, and list some proteins which have the same functions with LOR. You can find most of the proteins on our site.

Function	Related Protein
protein binding	GPR50;PGR;SDC2;TNFSF13B;DDX18;KRIT1;DNMT1;FZD5;DGCR8
protein binding, bridging	BCL3;FGG;FSCN1A;COL8A2;NEFH;ANK2;GATAD2A;IVL;PPP4R2
structural constituent of cytoskeleton	KRT2;CCDC6;TUBB5;TUBGCP3;TUBA7L;CTNNA2;KRT14;NEFL;HIP1
structural constituent of epidermis	KRT36;KRT84;LOR;PKP1
structural molecule activity	COPG;LMNB1;CLDN11;CLDN23;SNTB1;GNL1;MAP7D2A;CLDN2;DSP

LOR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LOR here. Most of them are supplied by our site. Hope this information will be useful for your research of LOR.

VIM

Son, ED; Kim, HJ; et al. Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion. JOURNAL OF DERMATOLOGICAL SCIENCE 74:64-71(2014).

Ben-Horin, S; et al. Loss of Response to Anti-Tumor Necrosis Factors: What Is the Next Step?. DIGESTIVE DISEASES 32:384-388(2014).