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Official Full Name lysyl oxidase-like 3
Background This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the;biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first;step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus;end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function.;The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor;suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript;variants of this gene have been reported but their full-length nature has not been determined.
Synonyms LOXL3; lysyl oxidase-like 3; LOXL; lysyl oxidase homolog 3; lysyl oxidase-like protein 3; EC
    • Species :
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human LOXL3-132H Recombinant Human LOXL3, GST-tagged Sf9 Insect Cell GST
    Human LOXL3-1979H Recombinant Human Lysyl Oxidase-Like 3, His-tagged CHO His
    Human LOXL3-277H Recombinant Human LOXL3 Protein, His-tagged E.coli His
    Human LOXL3-4730H Recombinant Human LOXL3 Protein, GST-tagged Wheat Germ GST
    Mouse Loxl3-278M Recombinant Mouse Loxl3 Protein, His-tagged E.coli His
    Mouse LOXL3-9187M Recombinant Mouse LOXL3 Protein Mammalian Cell His

    LOXL3 involved in several pathways and played different roles in them. We selected most pathways LOXL3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with LOXL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of collagen fibrils and other multimeric structures COL11A1B; MMP20; COL8A1A; COL2A1; CTSS; TLL2; CD151; COL6A3; CTSL2; TLL1
    Collagen formation LOXL3; LOXL2; SERPINH1; COL17A1A; CTSL2; LOXL4; COL1A2; COL5A2; PPIB; COL4A6
    Crosslinking of collagen fibrils PCOLCE; BMP1B; LOXL1; BMP1; LOXL4; LOX; TLL2; LOXL2; ABHD1; BMP1A
    Elastic fibre formation LOXL4; EFEMP2; LOXL1; MFAP2; FBN2; MFAP1; FBLN1; MFAP1B; BMP10; LTBP4
    Extracellular matrix organization MFAP4; TTR; CRTAP; FBLN2; F11R.2; LOXL1; ADAMTS5; LOXL3; ADAM15; COL2A1

    LOXL3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by LOXL3 itself. We selected most functions LOXL3 had, and list some proteins which have the same functions with LOXL3. You can find most of the proteins on our site.

    Function Related Protein
    copper ion binding ATP7B; POLR1B; CP; F8; PRNP; ADNP; TYR; CCC2; TYRP1B; CUTC
    protein binding C7orf25; HEATR5B; SPA17; CCNE1; NOD1; SMN2; AGT; GLRB; RAB5B; MXD4
    protein-lysine 6-oxidase activity LOXL2B; LOX; POLR1B; LOXL4; ABHD1; LOXL3; LOXL2A; LOXL2
    scavenger receptor activity CFI; POLR1B; LOXL2B; ACKR4; C8orf84; MARCO; SCARF2; SRCRB4D; VTNB; SCARA3

    LOXL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LOXL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of LOXL3.


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