Recombinant Human LOXL3 Protein, GST-tagged

• Cat.No.: LOXL3-4730H
• Product Overview: Human LOXL3 partial ORF ( NP_115992, 171 a.a. - 270 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: IRPAVGWGRRPLPVTEGLVEVRLPD GWSQVCDKGWSAHNSHVVCGMLGFP SEKRVNAAFYRLLAQRQQHSFGLHG VACVGTEAHLSLCSLEFYRANDTAR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LOXL3 lysyl oxidase-like 3 [ Homo sapiens ]
• Official Symbol: LOXL3
• Synonyms: LOXL3; lysyl oxidase-like 3; lysyl oxidase homolog 3; lysyl oxidase-like protein 3; LOXL
• Gene ID: 84695
• mRNA Refseq: NM_032603
• Protein Refseq: NP_115992
• MIM: 607163
• UniProt ID: P58215