Recombinant Human LOXL3 Protein, His-tagged

• Cat.No.: LOXL3-277H
• Product Overview: Recombinant Human LOXL3(Thr519~Asn726) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a lysyl oxidase, which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate, spine deformity, and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Molecular Mass: 27.7kDa
• Protein length: Thr519~Asn726
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 92%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: LOXL3 lysyl oxidase-like 3 [ Homo sapiens ]
• Official Symbol: LOXL3
• Synonyms: LOXL3; lysyl oxidase-like 3; lysyl oxidase homolog 3; lysyl oxidase-like protein 3; LOXL
• Gene ID: 84695
• mRNA Refseq: NM_032603
• Protein Refseq: NP_115992
• MIM: 607163
• UniProt ID: P58215