MANBA Protein, mannosidase, beta A, lysosomal


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Official Full Name mannosidase, beta A, lysosomal
Background This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.
Synonyms MANBA; mannosidase, beta A, lysosomal; beta-mannosidase; mannase; mannanase; lysosomal beta A mannosidase; MANB1
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MANBA-4523HCL Recombinant Human MANBA 293 Cell Lysate HEK293 N/A
    Mouse MANBA-9489M Recombinant Mouse MANBA Protein Mammalian Cell His
    Rat MANBA-3552R Recombinant Rat MANBA Protein Mammalian Cell His
    Zebrafish MANBA-10506Z Recombinant Zebrafish MANBA Mammalian Cell His

    MANBA involved in several pathways and played different roles in them. We selected most pathways MANBA participated on our site, such as Other glycan degradation, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MANBA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Other glycan degradation AGA; NEU1; MAN2B1; ENG-1; NEU3.3; GBA; HEXB; NEU4; FUCA1.1; NEU3.2
    Lysosome CTSA; SLC11A2; CTSC; ARSG; AP4M1; CD63; TCEAL4; NPC1; CTSZ; LAPTM4A

    MANBA has several biochemical functions, for example, beta-mannosidase activity, mannose binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MANBA itself. We selected most functions MANBA had, and list some proteins which have the same functions with MANBA. You can find most of the proteins on our site.

    Function Related Protein
    beta-mannosidase activity MANBA
    mannose binding MBL2; IGF2R; CD207; CD209C; LMAN1; MAN2B1; COLEC10; MANBA; MBL1; LMAN2

    MANBA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MANBA here. Most of them are supplied by our site. Hope this information will be useful for your research of MANBA.

    Pei, J; Kahl-McDonagh, M; et al. Brucella dissociation is essential for macrophage egress and bacterial dissemination. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 4:-(2014).
    Turse, JE; Pei, JW; et al. Lipopolysaccharide-deficient Brucella variants arise spontaneously during infection. FRONTIERS IN MICROBIOLOGY 2:-(2011).

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