MAP1B Protein, microtubule-associated protein 1B

MAP1B

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MAP1B

Official Full Name microtubule-associated protein 1B
Background This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are;thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene;is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain;and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important;role in development and function of the nervous system.
Synonyms MAP1B; microtubule-associated protein 1B; MAP5; MAP-1B; FUTSCH; FLJ38954; DKFZp686E1099; DKFZp686F1345
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAP1B-283H Recombinant Human MAP1B Mammalian Cell His
    Human MAP1B-8189H Recombinant Human MAP1B protein, His & T7-tagged E.coli His/T7
    Mouse Map1b-8190M Recombinant Mouse Map1b protein, His & T7-tagged E.coli His/T7
    Rat MAP1B-3556R Recombinant Rat MAP1B Protein Mammalian Cell His
    Rhesus Macaque MAP1B-2659R Recombinant Rhesus monkey MAP1B Protein, His-tagged Mammalian Cell His

    MAP1B involved in several pathways and played different roles in them. We selected most pathways MAP1B participated on our site, such as Lissencephaly gene (LIS1) in neuronal migration and development, Reelin signaling pathway, Regulation of Microtubule Cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Lissencephaly gene (LIS1) in neuronal migration and development KATNA1; NDEL1; DCX; LRPAP1; DYNLT1; NUDC; DAB1; MAP1B; VLDLR
    Reelin signaling pathway MAP1B; LRPAP1; VLDLR; DAB1
    Regulation of Microtubule Cytoskeleton MARK2; MARK1; DPYSL2; TESK2; TPPP; MAP1B; CFL2
    Wnt Signaling Pathway NetPath CSNK2A1P; TAX1BP3; PAX2; CRYBB2; TCF4; MARK2; MTAP1B; MAP1B; ROR2; NR5A1

    MAP1B has several biochemical functions, for example, microtubule binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP1B itself. We selected most functions MAP1B had, and list some proteins which have the same functions with MAP1B. You can find most of the proteins on our site.

    Function Related Protein
    microtubule binding KIF3A; NUSAP1; PRC1; GAS2L2; KIF12; HOOK3; APC; ZNF207; KIF1C; DYNC1I1
    protein binding GOSR2; VGLL2; RPP25L; HLA-DRB3; UBA1; DDB1; CLN6; FBXO6; PYGB; SERPINC1
    structural molecule activity CLTCA; CLTA; MAP1B; SPRR2H; SNTB1; KRT93; KRTAP3-1; KRT76; KRT31; MTAP7D3

    MAP1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP1B here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP1B.

    STK4; MAP1LC3B; TP53; RASSF5; GAN

    El Fatimy, R; Tremblay, S; et al. Fragile Mental Retardation Protein Interacts with the RNA-Binding Protein Caprin1 in Neuronal RiboNucleoProtein Complexes. PLOS ONE 7:-(2012).
    Rudrabhatla, P; Jaffe, H; et al. Direct evidence of phosphorylated neuronal intermediate filament proteins in neurofibrillary tangles (NFTs): phosphoproteomics of Alzheimer's NFTs. FASEB JOURNAL 25:3896-3905(2011).

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