|Official Full Name||mitogen-activated protein kinase kinase kinase 15|
|Background||The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses.|
|Synonyms||MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MAPK/ERK kinase kinase 15; MEK kinase 15; MEKK 15; Mitogen activated protein kinase kinase kinase 15; OTTHUMP00000183504; OTTHUMP00000183505; OTTHUMP00000224565; apoptosis signal-regulating kinase 3; ASK3|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
MAP3K15 involved in several pathways and played different roles in them. We selected most pathways MAP3K15 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP3K15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
MAP3K15 has several biochemical functions, for example, ATP binding, MAP kinase kinase kinase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP3K15 itself. We selected most functions MAP3K15 had, and list some proteins which have the same functions with MAP3K15. You can find most of the proteins on our site.
|ATP binding||NEK10; ABCF3; ATAD1; NLRP12; SLFN5; CKMT1B; MCMDC2; TAP2; PAK2; RFK|
|MAP kinase kinase kinase activity||MAP3K8; STK3; TAOK2; MAP3K13; EGFR; MAP3K4; RAF1; MAP3K14; KIAA1804; YSK4|
|metal ion binding||UNC13C; LMX1BA; XPNPEP2; ZNF397; LHX2A; GMEB1; NGB; CXXC1B; ZFP746; TCN2|
MAP3K15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP3K15 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP3K15.
PRKAB2; HSP90AB1; CDC37; cysJ