Recombinant Human MAP3K15, GST-tagged

Cat.No. : MAP3K15-44H
Product Overview : Recombinant human ASK3 (MAP3K15) (582-1169) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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Description : ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses. ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
Source : Sf9 insect cells using baculovirus
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass : ~93 kDa
Applications : Western Blot
Storage : Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1ug/ul
Gene Name : MAP3K15 mitogen-activated protein kinase kinase kinase 15 [ Homo sapiens ]
Official Symbol : MAP3K15
Synonyms : MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MEKK 15; MEK kinase 15; MAPK/ERK kinase kinase 15; apoptosis signal-regulating kinase 3; ASK3;
Gene ID : 389840
mRNA Refseq : NM_001001671
Protein Refseq : NP_001001671
MIM : 300820
UniProt ID : Q6ZN16
Chromosome Location : Xp22.12
Function : ATP binding; MAP kinase kinase kinase activity; metal ion binding; nucleotide binding; protein serine/threonine kinase activity;

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