Recombinant Human MAP3K15, GST-tagged

• Cat.No.: MAP3K15-44H
• Product Overview: Recombinant human ASK3 (MAP3K15) (582-1169) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses. ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
• Source: Sf9 insect cells using baculovirus
• Species: Human
• Tag: GST
• Form: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~93 kDa
• Applications: Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1ug/ul

Gene Information

• Gene Name: MAP3K15 mitogen-activated protein kinase kinase kinase 15 [ Homo sapiens ]
• Official Symbol: MAP3K15
• Synonyms: MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MEKK 15; MEK kinase 15; MAPK/ERK kinase kinase 15; apoptosis signal-regulating kinase 3; ASK3
• Gene ID: 389840
• mRNA Refseq: NM_001001671
• Protein Refseq: NP_001001671
• MIM: 300820
• UniProt ID: Q6ZN16
• Chromosome Location: Xp22.12
• Function: ATP binding; MAP kinase kinase kinase activity; metal ion binding; nucleotide binding; protein serine/threonine kinase activity