Recombinant Human MAP3K15, GST-tagged
Cat.No. : | MAP3K15-44H |
Product Overview : | Recombinant human ASK3 (MAP3K15) (582-1169) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
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Description : | ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses. ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~93 kDa |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1ug/ul |
Gene Name : | MAP3K15 mitogen-activated protein kinase kinase kinase 15 [ Homo sapiens ] |
Official Symbol : | MAP3K15 |
Synonyms : | MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MEKK 15; MEK kinase 15; MAPK/ERK kinase kinase 15; apoptosis signal-regulating kinase 3; ASK3; |
Gene ID : | 389840 |
mRNA Refseq : | NM_001001671 |
Protein Refseq : | NP_001001671 |
MIM : | 300820 |
UniProt ID : | Q6ZN16 |
Chromosome Location : | Xp22.12 |
Function : | ATP binding; MAP kinase kinase kinase activity; metal ion binding; nucleotide binding; protein serine/threonine kinase activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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