map3k9
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  • Official Full Name
  • mitogen-activated protein kinase kinase kinase 9
  • Background
  • Mixed-lineage kinases (MLKs) belong to the mitogen activated kinase kinase kinase (MAPKKK) family of dual-specificity protein kinases. While not particularly well conserved at the sequence level, MLK1, 2 and 3 share a conserved domain structure consisting
  • Synonyms
  • MAP3K9; mitogen-activated protein kinase kinase kinase 9; MLK1; MEKK9; PRKE1; mixed lineage kinase 1 (tyr and ser/thr specificity)
Cat.#:MAP3K9-9519MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MAP3K9 Protein
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Cat.#:MAP3K9-1040HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-Tagged
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Cat.#:MAP3K9-1262HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 9, GST-tagged
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Involved Pathway

MAP3K9 involved in several pathways and played different roles in them. We selected most pathways MAP3K9 participated on our site, such as Insulin Signaling, p38 MAPK Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAP3K9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Insulin Signaling
STXBP4; STXBP1A; GRB14; GRB10; STXBP3A; SNAP25A; REG1A; FLOT1; INPP4AA; RHOJ
p38 MAPK Signaling Pathway
MAP3K9; GADD45G; MAP3K10

Protein Function

MAP3K9 has several biochemical functions, for example, ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAP3K9 itself. We selected most functions MAP3K9 had, and list some proteins which have the same functions with MAP3K9. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CDK15; ACLYA; ABCA3; UBE2L3B; HSPD1; SMARCA5; MAGI1; ABCD3A; ATP11A; TTLL3
Function JUN kinase kinase kinase activity
Related Protein MAP3K1; MAP3K11; MAP3K9; ALPK2; MAP3K10
Function MAP kinase kinase activity
Related Protein ALPK2; MAP2K2B; MAP2K7; MAP3K9; MAP2K1; LRRK2; MAP3K20; MAP2K6; MAP2K2A; MAPK10
Function protein binding
Related Protein EDDM3B; CRYGD; CLK3; KIF5B; HECTD3; FAM60A; PATL1; FBXO7; IGHMBP2; FCER1G
Function protein homodimerization activity
Related Protein CAMK2G; AP1S2; NR0B1; DEM1; ATP2A1; GZMA; UGT1A7; PVRL2L; CARS; SNX1
Function protein serine/threonine kinase activity
Related Protein SRPK2; PRKCHA; PRKCDA; MAP3K11; RPS6KA5; ARAF; STK32B; ATM; SLK; MAP2K7
Function protein tyrosine kinase activity
Related Protein CLK4; MAP2K7; ZAP70; EPHB3A; JAK3; ERBB2; INSRA; KITA; MAP2K5; BLK

Interacting Protein

MAP3K9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAP3K9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAP3K9.
HSP90AB1; abl-tide

MAP3K9 Related Articles

Sharaf, H; Matou-Nasri, S; et al. Advanced glycation endproducts increase proliferation, migration and invasion of the breast cancer cell line MDA-MB-231. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1852:429-441(2015).
Jeon, JH; Kim, YH; et al. Bacillus anthracis genomic DNA enhances lethal toxin-induced cytotoxicity through TNF-alpha production. BMC MICROBIOLOGY 14:-(2014).