MED16 Protein, mediator complex subunit 16


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Official Full Name mediator complex subunit 16
Background Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.
Synonyms MED16; mediator complex subunit 16; THRAP5, thyroid hormone receptor associated protein 5; mediator of RNA polymerase II transcription subunit 16; DRIP92; TRAP95; DRIP 92; MED 16; THRAP 5; Thyroid hormone receptor associated protein 5; Thyroid hormone receptor associated protein complex 95 kDa component; Trap 95; Vitamin D3 receptor interacting protein complex component; thyroid hormone receptor-associated protein 5; thyroid hormone receptor-associated protein, 95-kD subunit; vitamin D3 receptor-interacting protein complex 92 kDa component; thyroid hormone receptor-assoc; THRAP5
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MED16-31175TH Recombinant Human MED16, His-tagged E.coli His
    Human MED16-4477H Recombinant Human MED16 Protein, GST-tagged Wheat Germ GST
    Zebrafish MED16-7886Z Recombinant Zebrafish MED16 Mammalian Cell His

    MED16 involved in several pathways and played different roles in them. We selected most pathways MED16 participated on our site, such as Developmental Biology, Fatty acid, triacylglycerol, and ketone body metabolism, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology DCC; CRMP1; TDGF1; SEMA3A; COL4A4; DUSP5; SHB; DOCK1; ACTR3; DPYSL2
    Fatty acid, triacylglycerol, and ketone body metabolism PPARGC1B; MED10; GLIPR1; SLC25A1; MED31; ELOVL1A; ESRRA; THEM5; CPT1B; ACOT11A
    Gene Expression GATAD2AB; ZNF302; USP9X; ZNF726; TET2; NR5A1A; ADAT2; ZNF189; NR2F1; ZNF664
    Generic Transcription Pathway ZNF225; NRBF2; ZNF398; NR2F1A; HBXIP; NR1D2; ZNF738; NR2E3; PRDX2; RNF111
    Metabolism IP6K3; NUDT3; KCNC2; ACOT6; CYP2N13; HAS3; PDP1; PIK3R6; DPEP2; SACM1L
    Metabolism of lipids and lipoproteins FA2H; ALOX5B.3; SCP2B; MED31; COQ6; CERS5; CYP4F22; MED19; ACOT9; MED16
    PPARA activates gene expression MTF1; GRHL1; MED16; MED6; MED22; MED8; SREBF2; G0S2; MED25; CTGF
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) G0S2; MED7; GRHL1; PLIN2; MED10; MED25; CDK19; CTGF; MED19; MTF1

    MED16 has several biochemical functions, for example, catalytic activity, protein binding, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED16 itself. We selected most functions MED16 had, and list some proteins which have the same functions with MED16. You can find most of the proteins on our site.

    Function Related Protein
    catalytic activity RDH7; PPTC7A; PCXA; DIP2BA; TGM3; ALDH1L1; PKM; NDUFA9A; PPM1LA; ALPI.2
    protein binding CCDC101; WWTR1; ERP29; GOLGA3; FTL; SYT11; FAM103A1; ZFYVE27; DIRAS3; BCAM
    receptor activity SMAGP; VMN1R43; SELS; GRIA4A; GUCY1B3; CD5; NLGN1; TLR3; CD4; GFRA1B
    thyroid hormone receptor binding TRIP12; MED1; NCOR1; FUS; MED16; MED17; MED13; TAF11; NUP62; MED24
    thyroid hormone receptor coactivator activity MED1; MED16; ACTN2; NCOA2
    transcription coactivator activity RNF20; RB1; SUB1B; MTDH; RXRB; JUNB; MED20; MED21; KMT2E; MNT
    transcription cofactor activity SND1; ZFP865; MED12; CALCOCO1; LDB2A; HES6; POU2AF1; RFXANK; SLC26A3; MED4
    vitamin D receptor binding TAF11; MED30; RXRA; MED14; MED4; MED16; RUNX2B; SNW1; THRAP3; MED1

    MED16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED16.

    MED10; MED19; CDK19; MED26; MED9; MED14; MED24; MED25

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