|Official Full Name||myeloid/lymphoid or mixed-lineage leukemia 4|
|Background||This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.|
|Synonyms||MLL4; myeloid/lymphoid or mixed-lineage leukemia 4; histone-lysine N-methyltransferase MLL4; KMT2D; WBP-7; trithorax homolog 2; trithorax homologue 2; WW domain binding protein 7; WW domain-binding protein 7; lysine N-methyltransferase 2D; mixed lineage l|
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MLL4 involved in several pathways and played different roles in them. We selected most pathways MLL4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MLL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
MLL4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MLL4 itself. We selected most functions MLL4 had, and list some proteins which have the same functions with MLL4. You can find most of the proteins on our site.
MLL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLL4.