MLL5
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Official Full Name
myeloid/lymphoid or mixed-lineage leukemia 5 -
Synonyms
Kmt2E;1810033J14Rik;9530077A04Rik;D230038D11Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MLL5-9883M | Recombinant Mouse MLL5 Protein | Mammalian Cells | Mouse | His |
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| MLL5-5583M | Recombinant Mouse MLL5 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| MLL5-5583M-B | Recombinant Mouse MLL5 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
MLL5 involved in several pathways and played different roles in them. We selected most pathways MLL5 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | DOT1L,PLOD2,GCDH,DLST,SETD1BA,ALDH2.2,ALDH1B1,ACAT1,SETD1B,MLL1 |
Protein Function
MLL5 has several biochemical functions, for example, enzyme binding,histone methyltransferase activity (H3-K4 specific),histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MLL5 itself. We selected most functions MLL5 had, and list some proteins which have the same functions with MLL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CNOT6,ROCK1,PLCD3A,ZNF643,YY1B,ZNFL1,MMP14B,GALNT13,ZMYND10,FBP1 |
| histone-lysine N-methyltransferase activity | EHMT1B,SETD7,SETD8A,PRDM2,AAAS,PRDM6,SMYD1,EZH1,MLL1,EZH2 |
| histone methyltransferase activity (H3-K4 specific) | WDR82,SETMAR,KMT2A,WHSC1L1,SETD3,KMT2E,MLL1,ASH1L,WBP7,SMYD1B |
| enzyme binding | GSTM2,HSPA1A,PHB,TSPAN33,NPC2,THRB,HSPA1B,HMGA1-RS1,CTNNBL1,ATXN10 |
| zinc ion binding | ZNRF2,RUNX1,CTCF,INTS12,FBXO30,WHSC1L1,ZRANB1,ZCCHC8,PHC2,AJUBA |
| transferase activity | KDRL,KITA,ZDHHC16B,BMPR2B,IGF1RA,ELOVL4A,FLJ11011L,BAIAP2L1A,AKT3A,PRKG1A |
| transcription coactivator activity | GRIP1,SMARCC2,RNF14,BRD7,PQBP1,PRDM16,CEBPA,SOX10,MAML2,MED14 |
| methyltransferase activity | METTL8,COMTB,RG9MTD1,SKINT8,SMYD2A,TRMT10B,METTL23,PRMT3,DNMT4,CIAPIN1 |
Interacting Protein
MLL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLL5.
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