mmp10
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  • Official Full Name
  • matrix metallopeptidase 10 (stromelysin 2)
  • Background
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Synonyms
  • MMP10; matrix metallopeptidase 10 (stromelysin 2); SL-2; STMY2; stromelysin-2; MMP-10; transin 2; transin-2; stromelysin 2; matrix metalloprotease 10; matrix metalloproteinase-10; matrix metalloproteinase 10 (stromelysin 2)
Cat.#:MMP10-5415HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MMP10 Protein, GST-tagged
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Cat.#:MMP10-156HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human matrix MMP10 (Stromelysin 2), Catalytic Domain
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Cat.#:MMP10-440HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human matrix metallopeptidase 10 (stromelysin 2), His-tagged
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Cat.#:MMP10-5041HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP10, His-tagged
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Cat.#:Mmp10-727MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mmp10 protein, His & T7-tagged
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Cat.#:MMP10-3710RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MMP10 Protein
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Cat.#:Mmp10-728RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mmp10 protein, His & T7-tagged
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Cat.#:MMP10-5355CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MMP10
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Cat.#:MMP10-4282HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MMP10 293 Cell Lysate
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Involved Pathway

MMP10 involved in several pathways and played different roles in them. We selected most pathways MMP10 participated on our site, such as Activation of Matrix Metalloproteinases, Collagen degradation, Degradation of the extracellular matrix, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP10 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of Matrix Metalloproteinases
MMP24; CMA1; ELANE; FURINB; MMP13; TIMP2B; MMP11; TPSAB1; CTSL2; LOC100686744
Collagen degradation
MGC174152; COL9A3; CTSB; MMP12; MMP13; MMP15; COL19A1; CTS7; MGC174857; ADAM9
Degradation of the extracellular matrix
MMP12; CTSL2; ADAM15; COL23A1; KLK7; TLL2; ADAMTS18; COL9A1; NID1; CTSD
Extracellular matrix organization
COL5A2; LTBP3; CD151; CTS7; PCOLCE; TIMP2B; LTBP4; MATN3B; COL9A1A; DDR1
Matrix Metalloproteinases
MMP12; MMP19; TIMP4; MMP11; MMP15; MMP10; TIMP2; MMP26; MMP17; MMP8

Protein Function

MMP10 has several biochemical functions, for example, calcium ion binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP10 itself. We selected most functions MMP10 had, and list some proteins which have the same functions with MMP10. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein PCDH2AB11; ANXA6; SCUBE3; CHP1; PCDH1; PCDHB13; COMP; CRB2B; DNER; PVALB9
Function metalloendopeptidase activity
Related Protein ADAMTS8; YME1L1; UQCRC1; ADAM17; MEP1A.1; C6AST4; MMP13; PAPPAB; THOP1; SPG7
Function zinc ion binding
Related Protein RNF126; RORA; PHEX; SUPT4H1; MUL1; ING3; PDZRN4; LIMCH1B; RNF181; CPXM2

MMP10 Related Articles

Yeo, ASL; Azhar, NA; et al. Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes. PLOS ONE 9:-(2014).
Bernal-Lopez, MR; Garrido-Sanchez, L; et al. Antioxidized LDL Antibodies Are Associated With Different Metabolic Pathways in Patients With Atherosclerotic Plaque and Type 2 Diabetes. DIABETES CARE 36:1006-1011(2013).

MMP10 Related Gene Family

MMPs