MRPL21

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MRPL21

Official Full Name mitochondrial ribosomal protein L21
Background Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).
Synonyms MRPL21; mitochondrial ribosomal protein L21; 39S ribosomal protein L21, mitochondrial; 39S ribosomal protein L21, mitochondrial precursor; mitochondrial; 39S ribosomal protein L21; L21mt; MGC62013; MRP L21; MRP-L21; RM21_HUMAN
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MRPL21-4188HCL Recombinant Human MRPL21 293 Cell Lysate HEK293 N/A
    Human MRPL21-5566H Recombinant Human MRPL21 Protein, GST-tagged Wheat Germ GST
    Human MRPL21-989H Recombinant Human MRPL21, His-tagged E.coli His
    Chicken MRPL21-4357C Recombinant Chicken MRPL21 Mammalian Cell His
    Zebrafish MRPL21-4742Z Recombinant Zebrafish MRPL21 Mammalian Cell His

    MRPL21 involved in several pathways and played different roles in them. We selected most pathways MRPL21 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome RPL27A; RPL5; RPS29; RPLP0; RPS26; MRPL21; RPS10; MRPS17; RPL29; RPL4

    MRPL21 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL21 itself. We selected most functions MRPL21 had, and list some proteins which have the same functions with MRPL21. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding ABT1; ESF1; EIF4G3; SEC63; CCDC9; RBM28; NTPCR; ZC3H10; SRPK1; ITM2B
    structural constituent of ribosome RPS14; MRP63; MRPS21; MRPS23; RPS11; RPL28; RPS23; MRPL51; RPS6; RPS5

    MRPL21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL21 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL21.

    Brwd3; C1qbp; ICT1; MRPL50; MRPL9; MRPL1

    Ueda, M; Kadowaki, KI; et al. Gene Content and Gene Transfer from Mitochondria to the Nucleus During Evolution. MITOCHONDRIAL GENOME EVOLUTION 63:21-40(2012).
    Portereiko, MF; Sandaklie-Nikolova, L; et al. Nuclear fusion defective1 encodes the Arabidopsis RPL21M protein and is required for karyogamy during female gametophyte development and fertilization. PLANT PHYSIOLOGY 141:957-965(2006).

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