Recombinant Human MRPL21 Protein, GST-tagged

• Cat.No.: MRPL21-5566H
• Product Overview: Human MRPL21 full-length ORF ( AAH55088, 1 a.a. - 209 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 48.73 kDa
• AA Sequence: MAAAMAASSLTVTLGRLASACSHSI LRPSGPGAASLWSASRRFNSQSTSY LPGYVPKTSLSSPPWPEVVLPDPVE ETRHHAEVVKKVNEMIVTGQYGRLF AVVHFASRQWKVTSEDLILIGNELD LACGERIRLEKVLLVGADNFTLLGK PLLGKDLVRVEATVIEKTESWPRII MRFRKRKNFKKKRIVTTPQTVLRIN SIEIAPCLL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MRPL21 mitochondrial ribosomal protein L21 [ Homo sapiens ]
• Official Symbol: MRPL21
• Synonyms: MRPL21; mitochondrial ribosomal protein L21; 39S ribosomal protein L21, mitochondrial; L21mt; MRP-L21; MGC62013
• Gene ID: 219927
• mRNA Refseq: NM_181514
• Protein Refseq: NP_852615
• MIM: 611834
• UniProt ID: Q7Z2W9