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MRPL39

Official Full Name

mitochondrial ribosomal protein L39
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.
Synonyms

MRPL39; mitochondrial ribosomal protein L39; RPML5; MRP-L5; PRED22; PRED66; FLJ20451;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL39-4173HCL	Recombinant Human MRPL39 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPL39-5705H	Recombinant Human MRPL39 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	MRPL39-5582H	Recombinant Human MRPL39 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPL39-6407HF	Recombinant Full Length Human MRPL39 Protein, GST-tagged	In Vitro Cell Free System	GST	333 amino acids	Inquiry
Mouse	MRPL39-10066M	Recombinant Mouse MRPL39 Protein	Mammalian Cell	His		Inquiry
Mouse	MRPL39-5701M-B	Recombinant Mouse MRPL39 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	MRPL39-5701M	Recombinant Mouse MRPL39 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Mrpl39-4156M	Recombinant Mouse Mrpl39 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	MRPL39-10284Z	Recombinant Zebrafish MRPL39	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPL39 involved in several pathways and played different roles in them. We selected most pathways MRPL39 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL39 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL38;MRPL3;GFM2;DAP3;PTCD3;MRPS23;MRPS35;MRPS34;MRPL47
Mitochondrial translation elongation	MRPL46;MRPL3;MRPS25;ICT1;MRPL47;PTCD3;GADD45GIP1;MRPS24;MRPS22
Mitochondrial translation initiation	CHCHD1;MRPL46;MRPL55;MRPL52;ICT1;MRPL51;MRPL50;MTFMT;MTIF3
Mitochondrial translation termination	MRPL39;MRPL42;MRPL55;MRPS27;MRPL50;MRPL54;MRPL3;PTCD3;MRPL41
Organelle biogenesis and maintenance	TTC26;DYNLL2A;TTC21B;ICT1;CLUAP1;TSFM;WDR19;SCLT1;MTIF3

MRPL39 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL39 itself. We selected most functions MRPL39 had, and list some proteins which have the same functions with MRPL39. You can find most of the proteins on our site.

Function	Related Protein
nucleotide binding	PCXA;RBM24A;CAMK1GB;DDX51;UBE2KB;GNAT1;DDX19;LMTK3;CAMKK1A
poly(A) RNA binding	NOC4L;SRSF7;EIF1B;EXOSC7;PHF5A;TSNAX;EIF2S1A;EWSR1;RPL5A

MRPL39 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL39 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL39.

PAN2; USP32; Gtf3c4; MRPL50; MRPL9; MRPL1; SIRT4; Mad2l1