mrps5
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  • Official Full Name
  • mitochondrial ribosomal protein S5
  • Background
  • Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q.
  • Synonyms
  • MRPS5; mitochondrial ribosomal protein S5; 28S ribosomal protein S5, mitochondrial; mitochondrial 28S ribosomal protein S5; MRP S5; S5mt; mitochondrial; 28S ribosomal protein S5; MRP-S5; RT05_HUMAN
Cat.#:MRPS5-5624HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MRPS5 Protein, GST-tagged
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Cat.#:MRPS5-1041HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MRPS5, GST-tagged
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Cat.#:MRPS5-4268CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MRPS5
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Cat.#:MRPS5-4492ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MRPS5
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Cat.#:MRPS5-4133HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MRPS5 293 Cell Lysate
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Involved Pathway

MRPS5 involved in several pathways and played different roles in them. We selected most pathways MRPS5 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ribosome
RPL15; MRPL22; MRPL4; RPL36A; MRPL36; RPS17L; RPS27; RPL18A; MRPS17; MRPL18

Protein Function

MRPS5 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS5 itself. We selected most functions MRPS5 had, and list some proteins which have the same functions with MRPS5. You can find most of the proteins on our site.
Function
Related Protein
Function poly(A) RNA binding
Related Protein NSUN2; SORBS2; SNRNP40; FKBP4; SLC25A5; RPS17L; RPL10L; USO1; NPM3; SNRPD3
Function structural constituent of ribosome
Related Protein MRPS15; RPL13; RPS21; RPL34; RPL23A; MRPS14; RPS24; MRPS22; MRPL23; MRPS35

Interacting Protein

MRPS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS5.
DDX56; C1qbp; SNX3; YBX1; MZT1; ICT1; ESR2; AGO1

MRPS5 Related Articles

Lee, J; Seol, MY; et al. A Metabolic Phenotype Based on Mitochondrial Ribosomal Protein Expression as a Predictor of Lymph Node Metastasis in Papillary Thyroid Carcinoma. MEDICINE 94:-(2015).
Zaspel, JM; Weller, SJ; et al. Phylogeny and Evolution of Pharmacophagy in Tiger Moths (Lepidoptera: Erebidae: Arctiinae). PLOS ONE 9:-(2014).