mtap
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  • Official Full Name
  • methylthioadenosine phosphorylase
  • Background
  • MTAP is an enzyme that is essential for the salvage pathway for both adenine and methionine synthesis. MTAP catalyzes the cleavage of 5'-methylthioadenosine into adenine and 5-methylthio-D-ribose-1-phosphate. Adenine is then used to generate AMP whereas 5
  • Synonyms
  • MTAP; methylthioadenosine phosphorylase; S-methyl-5-thioadenosine phosphorylase; c86fus; MSAP; MTAPase; MTA phosphorylase; MeSAdo phosphorylase; 5-methylthioadenosine phosphorylase
Cat.#:MTAP-386HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MTAP Protein, His-tagged
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Cat.#:Mtap-387HTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mtap Protein, His-tagged
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Cat.#:MTAP-5684HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MTAP Protein, GST-tagged
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Cat.#:MTAP-2005HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MTAP Protein, MYC/DDK-tagged
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Cat.#:MTAP-422HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Methylthioadenosine Phosphorylase, GST-tagged
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Cat.#:MTAP-29502THTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MTAP, GST-tagged
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Cat.#:MTAP-712CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus MTAP Protein, His-tagged
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Cat.#:MTAP-2892RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MTAP Protein, His-tagged
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Cat.#:MTAP-3242CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MTAP
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Cat.#:MTAP-10835ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MTAP
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Cat.#:MTAP-424HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human MTAP lysate
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Involved Pathway

MTAP involved in several pathways and played different roles in them. We selected most pathways MTAP participated on our site, such as Cysteine and methionine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTAP were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cysteine and methionine metabolism
GCLC; AGXT2; LDHAL6A; GOT2; AHCYL1; TAT; GOT2A; CTH; MAT2A; SDSL
Metabolic pathways
ACAA1A; ALG11; COX6C; FBP2; EPRS; ALG13; ADKB; AOX3; ITPKC; PIP5KL1

Protein Function

MTAP has several biochemical functions, for example, S-methyl-5-thioadenosine phosphorylase activity, phosphorylase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MTAP itself. We selected most functions MTAP had, and list some proteins which have the same functions with MTAP. You can find most of the proteins on our site.
Function
Related Protein
Function S-methyl-5-thioadenosine phosphorylase activity
Related Protein MTAP
Function phosphorylase activity
Related Protein PYGMB; TYMP; MTAP; PYGMA
Function protein binding
Related Protein PRDM13; HOMER2; FAM81B; RNASE1; ELN; INPP5A; RPAP3; ZFP423; ATM; NELL1

Interacting Protein

MTAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTAP here. Most of them are supplied by our site. Hope this information will be useful for your research of MTAP.
CENPH; LYRM1; NP; CDC25A; RELB; FOLH1; MAP1LC3A

MTAP Related Articles

Chidlow, G; Wood, JPM; et al. Ocular Expression and Distribution of Products of the POAG-Associated Chromosome 9p21 Gene Region. PLOS ONE 8:-(2013).
Meyer, S; Fuchs, TJ; et al. A Seven-Marker Signature and Clinical Outcome in Malignant Melanoma: A Large-Scale Tissue-Microarray Study with Two Independent Patient Cohorts. PLOS ONE 7:-(2012).