mus81
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  • Official Full Name
  • MUS81 endonuclease homolog (S. cerevisiae)
  • Background
  • Crossover junction endonuclease MUS81 is an enzyme that in humans is encoded by the MUS81 gene.
  • Synonyms
  • MUS81; MUS81 endonuclease homolog (S. cerevisiae); MUS81 endonuclease homolog (yeast); crossover junction endonuclease MUS81; FLJ44872; SLX3; SLX3 structure specific endonuclease subunit homolog (S. cerevisiae); FLJ21012; Mus 81; MUS81 Endonuclease Homolog; MUS81_HUMAN; OTTHUMP00000233867; OTTHUMP00000233868; OTTHUMP00000233869; OTTHUMP00000233949; SLX3 structure-specific endonuclease subunit homolog
Cat.#:MUS81-5757HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MUS81 Protein, GST-tagged
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Cat.#:MUS81-10261MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MUS81 Protein
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Cat.#:MUS81-3824RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MUS81 Protein
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Cat.#:MUS81-12677ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MUS81
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Cat.#:MUS81-4056HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MUS81 293 Cell Lysate
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Involved Pathway

MUS81 involved in several pathways and played different roles in them. We selected most pathways MUS81 participated on our site, such as Homologous recombination, Fanconi anemia pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUS81 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Homologous recombination
RPA3; RAD54B; POLD1; SHFM1; RAD51; RAD51D; FUZ; SSBP1; XRCC2; RAD51L3
Fanconi anemia pathway
BRIP1; ERCC1; EME2; RAD51C; USP36; C19orf40; FANCB; FANCC; PMS2; TELO2

Protein Function

MUS81 has several biochemical functions, for example, 3-flap endonuclease activity, DNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MUS81 itself. We selected most functions MUS81 had, and list some proteins which have the same functions with MUS81. You can find most of the proteins on our site.
Function
Related Protein
Function 3-flap endonuclease activity
Related Protein MUS81; FUZ
Function DNA binding
Related Protein POU3F2A; PATZ1; ASCL3; BANP; SYCP1; SSRP1; HIST2H2AC; KDM5BB; NKX3.3; HEMK1
Function metal ion binding
Related Protein FHL2B; CYP1D1; STK32C; TNFSF10; CAR1; TRIM35-22; TNKS2; REPIN1; ZFP319; ZBTB39
Function protein binding
Related Protein FAM81B; CARKD; APLP2; C16orf72; LDLRAD1; KIAA1530; ERLIN1; SMYD2; ARL6IP5; BLM

Interacting Protein

MUS81 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUS81 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUS81.
EME1; SLX4; FEN1; SLX1A