Recombinant Human MUS81 Protein, GST-tagged
Cat.No. : | MUS81-5757H |
Product Overview : | Human MUS81 full-length ORF ( NP_079404.2, 1 a.a. - 551 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks. [provided by RefSeq, Jun 2017] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 87.5 kDa |
AA Sequence : | MAAPVRLGRKRPLPACPNPLFVRWL TEWRDEATRSRHRTRFVFQKALRSL RRYPLPLRSGKEAKILQHFGDGLCR MLDERLQRHRTSGGDHAPDSPSGEN SPAPQGRLAEVQDSSMPVPAQPKAG GSGSYWPARHSGARVILLVLYREHL NPNGHHFLTKEELLQRCAQKSPRVA PGSAPPWPALRSLLHRNLVLRTHQP ARYSLTPEGLELAQKLAESEGLSLL NVGIGPKEPPGEETAVPGAASAELA SEAGVQQQPLELRPGEYRVLLCVDI GETRGGGHRPELLRELQRLHVTHTV RKLHVGDFVWVAQETNPRDPANPGE LVLDHIVERKRLDDLCSSIIDGRFR EQKFRLKRCGLERRVYLVEEHGSVH NLSLPESTLLQAVTNTQVIDGFFVK RTADIKESAAYLALLTRGLQRLYQG HTLRSRPWGTPGNPESGAMTSPNPL CSLLTFSDFNAGAIKNKAQSVREVF ARQLMQVRGVSGEKAAALVDRYSTP ASLLAAYDACATPKEQETLLSTIKC GRLQRNLGPALSRTLSQLYCSYGPL T |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MUS81 MUS81 endonuclease homolog (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | MUS81 |
Synonyms : | MUS81; MUS81 endonuclease homolog (S. cerevisiae); MUS81 endonuclease homolog (yeast); crossover junction endonuclease MUS81; FLJ44872; SLX3; SLX3 structure specific endonuclease subunit homolog (S. cerevisiae); SLX3 structure-specific endonuclease subunit homolog; FLJ21012; |
Gene ID : | 80198 |
mRNA Refseq : | NM_025128 |
Protein Refseq : | NP_079404 |
MIM : | 606591 |
UniProt ID : | Q96NY9 |
Products Types
◆ Recombinant Protein | ||
MUS81-3483R | Recombinant Rat MUS81 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mus81-4226M | Recombinant Mouse Mus81 Protein, Myc/DDK-tagged | +Inquiry |
MUS81-5816M | Recombinant Mouse MUS81 Protein, His (Fc)-Avi-tagged | +Inquiry |
MUS81-3824R | Recombinant Rat MUS81 Protein | +Inquiry |
MUS81-10261M | Recombinant Mouse MUS81 Protein | +Inquiry |
◆ Lysates | ||
MUS81-4056HCL | Recombinant Human MUS81 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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