mvd
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  • Official Full Name
  • mevalonate (diphospho) decarboxylase
  • Background
  • The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
  • Synonyms
  • MVD; mevalonate (diphospho) decarboxylase; diphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase; MPD; FP17780; MDDase; Mevalonate (diphospho)decarboxylase; MVD1_HUMAN; OTTHUMP00000175197; mevalonatepyrophosphate decarboxylase
Cat.#:MVD-2336HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MVD Protein, MYC/DDK-tagged
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Cat.#:MVD-5767HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MVD Protein, GST-tagged
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Cat.#:MVD-1569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Mevalonate (diphospho) Decarboxylase, His-tagged
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Cat.#:MVD-26959THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MVD, His-tagged
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Cat.#:MVD-30263THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MVD, His-tagged
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Cat.#:MVD-3827RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MVD Protein
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Cat.#:MVD-2910RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MVD Protein, His-tagged
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Cat.#:MVD-4051HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MVD 293 Cell Lysate
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Involved Pathway

MVD involved in several pathways and played different roles in them. We selected most pathways MVD participated on our site, such as Terpenoid backbone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MVD were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Terpenoid backbone biosynthesis
MVDA; IDI1; HMGCS2; GGPS1; FNTA; HMGCRA; PDSS1; ACAT1; ACAT2; FDPS
Metabolic pathways
TRIT1; GALNS; ATP6V1BA; ATP5D; UQCR11; UGT2B15; NDUFA9; PLCD1A; HADHAA; NMNAT3

Protein Function

MVD has several biochemical functions, for example, ATP binding, Hsp70 protein binding, diphosphomevalonate decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MVD itself. We selected most functions MVD had, and list some proteins which have the same functions with MVD. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PRKCQ; PIK3C2B; ATP2B2; KIF14; UBE2G1; SPS2; NAIP6; P2RX5; SMARCAL1; HK3
Function Hsp70 protein binding
Related Protein L7RN6; RPS3; TFRC; GPR37; C11orf73; TSACC; CDK1; DNAJC10; ST13; DNAJB2
Function diphosphomevalonate decarboxylase activity
Related Protein MVD; MVDA
Function protein homodimerization activity
Related Protein ACTN4; PAH; CRTAM; SYT16; TERFA; TPR; CEBPB; C1QB; APOA1BP; BCL11A

Interacting Protein

MVD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MVD here. Most of them are supplied by our site. Hope this information will be useful for your research of MVD.
GNB5; EEF1G; EIF4EBP1; CDK1; CTBP2; LRIF1; Med22; Smc3; SETD1B

MVD Related Articles

Wang, WJ; Sivakumar, W; et al. Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals. NEUROSURGICAL FOCUS 38:-(2015).
Zhang, J; Yang, JM; et al. Multiple antigenic polypeptide composed of heparanase B-cell epitopes shrinks human hepatocellular carcinoma in mice. ONCOLOGY REPORTS 33:1248-1256(2015).