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MVD

  • Official Full Name

    mevalonate (diphospho) decarboxylase

  • Overview

    The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
  • Synonyms

    MVD; mevalonate (diphospho) decarboxylase; diphosphomevalonate decarboxylase; mevalonate pyrophosphate decarboxylase; MPD; FP17780; MDDase; Mevalonate (diphospho)decarboxylase; MVD1_HUMAN; OTTHUMP00000175197; mevalonatepyrophosphate decarboxylase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MVD-26959TH Recombinant Human MVD, His-tagged E.coli His
Human MVD-1569H Recombinant Human Mevalonate (diphospho) Decarboxylase, His-tagged E.coli His
Human MVD-30263TH Recombinant Human MVD, His-tagged E.coli His 400 amino acids
Human MVD-4051HCL Recombinant Human MVD 293 Cell Lysate HEK293 N/A
Human MVD-576H Recombinant Human MVD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MVD-2336H Recombinant Human MVD Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human MVD-6583HF Recombinant Full Length Human MVD Protein, GST-tagged In Vitro Cell Free System GST 400 amino acids
Human MVD-5767H Recombinant Human MVD Protein, GST-tagged Wheat Germ GST
Mouse Mvd-4229M Recombinant Mouse Mvd Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat MVD-3827R Recombinant Rat MVD Protein Mammalian Cell His
Rat MVD-3486R Recombinant Rat MVD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MVD-3486R-B Recombinant Rat MVD Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MVD-2910R Recombinant Rhesus monkey MVD Protein, His-tagged Mammalian Cell His
Rhesus Macaque MVD-2729R Recombinant Rhesus Macaque MVD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MVD-2729R-B Recombinant Rhesus Macaque MVD Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MVD Related Articles

MVD involved in several pathways and played different roles in them. We selected most pathways MVD participated on our site, such as Terpenoid backbone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MVD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Terpenoid backbone biosynthesisZMPSTE24;FDPS;HMGCS1;IDI2;HMGCRB;MVD;FNTA;HMGCS2;ACAT1
Metabolic pathwaysGALNS;PANK1B;GGT1A;CMPK1;CYP2A12;MTMR1B;GFPT1;GBE1;FH

MVD has several biochemical functions, for example, ATP binding, Hsp70 protein binding, diphosphomevalonate decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MVD itself. We selected most functions MVD had, and list some proteins which have the same functions with MVD. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNLRP11;CDC34A;MARK2;DDX41;RUNX3;TTK;DHX34;PIM3;WEE1
Hsp70 protein bindingPPID;DNAJC2;STIP1;DNAJC10;ERN1;FAM119A;TFRC;DNAJA1;RNF207
diphosphomevalonate decarboxylase activityMVD;MVDA
protein homodimerization activityLCN2;SIAH1A;TSG101;MTUS2;TCF4;VEGFB;GABPB2;DPYD;MSH2

MVD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MVD here. Most of them are supplied by our site. Hope this information will be useful for your research of MVD.

GNB5; EEF1G; EIF4EBP1; CDK1; CTBP2; LRIF1; Med22; Smc3; SETD1B

Wang, WJ; Sivakumar, W; et al. Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals. NEUROSURGICAL FOCUS 38:-(2015).
Zhang, J; Yang, JM; et al. Multiple antigenic polypeptide composed of heparanase B-cell epitopes shrinks human hepatocellular carcinoma in mice. ONCOLOGY REPORTS 33:1248-1256(2015).
  • Q&As
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