MYL3

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MYL3

Official Full Name myosin, light chain 3, alkali; ventricular, skeletal, slow
Background MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.
Synonyms MYL3; myosin, light chain 3, alkali; ventricular, skeletal, slow; myosin, light polypeptide 3, alkali; ventricular, skeletal, slow; myosin light chain 3; CMH8; MLC1SB; MLC1V; VLC1; CMLC1; cardiac myosin light chain 1; ventricular/slow twitch myosin alkali
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Myl3-4251M Recombinant Mouse Myl3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MYL3-5033H Recombinant Human MYL3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human MYL3-1134H Recombinant Human MYL3, GST-tagged E.coli GST
    Human MYL3-4027HCL Recombinant Human MYL3 293 Cell Lysate HEK293 N/A
    Human MYL3-5809H Recombinant Human MYL3 Protein, GST-tagged Wheat Germ GST
    Human MYL3-8027H Recombinant Human MYL3 protein, His-tagged E.coli His
    Mouse MYL3-10315M Recombinant Mouse MYL3 Protein Mammalian Cell His
    Mouse Myl3-8028M Recombinant Mouse Myl3 protein, His & GST-tagged E.coli His/GST
    Rat MYL3-3855R Recombinant Rat MYL3 Protein Mammalian Cell His
    Chicken MYL3-6715C Recombinant Chicken MYL3 Mammalian Cell His

    MYL3 involved in several pathways and played different roles in them. We selected most pathways MYL3 participated on our site, such as Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, Hypertrophic cardiomyopathy (HCM), which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cardiac muscle contraction ATP1B2A; CACNA1D; COX7A2A; COX7B2; CACNB3; COX8C; UQCRC2A; ACTC1B; ACTC1A; CACNG7A
    Adrenergic signaling in cardiomyocytes CACNG3; PPP2R5C; PIK3R2; ATP2B2; CACNG8; CACNA2D1; TNNI3; CAMK2D; CACNB3A; CAMK2G1
    Hypertrophic cardiomyopathy (HCM) ITGB6; ITGA3; ITGB8; ITGA8; ACTC1; TGFB1; DMD; TGFB3; CACNA2D4; ITGA9
    Dilated cardiomyopathy ITGB5; CACNB1; ITGA5; ACTG1; ITGB4; TPM3; MYL3; TTN; ITGA1; CACNB4

    MYL3 has several biochemical functions, for example, actin monomer binding, calcium ion binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL3 itself. We selected most functions MYL3 had, and list some proteins which have the same functions with MYL3. You can find most of the proteins on our site.

    Function Related Protein
    actin monomer binding ABL1; MKL1B; COBLL1; KLHL8; TWF1; PRKCE; PFN4; PFN2; TWF2; ABL2
    calcium ion binding DAG1; FAT1A; PCDH2G17; RGN; EFCAB5; PVALB1; SPTA1; EFEMP1; SWAP70B; PLA2G2F
    motor activity MYO1E; MYO1A; SMYHC1; MYO1H; MYO6; MYO6B; MYL6; MYH4; DYNC1I1; MYH1
    myosin II heavy chain binding MYL4; MYL3
    structural constituent of muscle MYBPH; MYOT; COX4I2; TPM2; PLEC; ANKRD2; ASPH; OBSCN; MYL3; TCAP

    MYL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL3.

    Mylk; FTH1; ATG101; YWHAZ

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